This manuscript is the second part of a two-part description of the current status of
understanding of the network function of the brain in health and disease. We start with the …

Changes in both brain structure and neurophysiological function regulating homotopic as
well as heterotopic interhemispheric interactions (IHIs) are assumed to be responsible for …

Voluntary movements depend on a well-regulated interplay between the primary motor
cortex (M1) and premotor areas. While to date the neural underpinnings of hand movements …

After stroke, movements of the paretic hand rely on altered motor network dynamics typically
including additional activation of the contralesional primary motor cortex (M1). The functional …

Both increases and decreases in resting state functional connectivity have been previously
observed within the motor network during aging. Moreover, the relationship between altered …

Neural interactions between contralateral motor regions are thought to be instrumental in the
successful preparation, and execution, of volitional movements. Here we investigated …

Background The dorsal premotor cortex (PMd) is a key region in bimanual coordination.
However, causal evidence linking PMd functionality during motor planning and execution to …

Hemiparesis after stroke is associated with increased neural activity not only in the lesioned
but also in the contralesional hemisphere. While most studies have focused on the role of …

Healthy aging is accompanied by changes in brain activation patterns in the motor system.
In older subjects, unilateral hand movements typically rely on increased recruitment of …

The aim of the present study was to investigate whether there is a functional difference in
short-latency (SIHI) and long-latency (LIHI) interhemispheric inhibition from the active to the …