[HTML][HTML] Antiviral drug discovery: preparing for the next pandemic

CS Adamson, K Chibale, RJM Goss… - Chemical Society …, 2021 - pubs.rsc.org
Clinically approved antiviral drugs are currently available for only 10 of the more than 220
viruses known to infect humans. The SARS-CoV-2 outbreak has exposed the critical need …

Review of emerging pharmacotherapy for the treatment of coronavirus disease 2019

A Barlow, KM Landolf, B Barlow… - … : The Journal of …, 2020 - Wiley Online Library
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has
evolved into an emergent global pandemic. Coronavirus disease 2019 (COVID‐19) can …

SARS-CoV-2: recent reports on antiviral therapies based on lopinavir/ritonavir, darunavir/umifenovir, hydroxychloroquine, remdesivir, favipiravir and other drugs for …

M Costanzo, MAR De Giglio… - Current medicinal …, 2020 - ingentaconnect.com
Here we report on the most recent updates on experimental drugs successfully employed in
the treatment of the disease caused by SARS-CoV-2 coronavirus, also referred to as COVID …

Convalescent plasma therapy for COVID-19: state of the art

D Focosi, AO Anderson, JW Tang… - Clinical microbiology …, 2020 - Am Soc Microbiol
Convalescent plasma (CP) therapy has been used since the early 1900s to treat emerging
infectious diseases; its efficacy was later associated with the evidence that polyclonal …

Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements

A Pandey, AN Nikam, AB Shreya, SP Mutalik… - Life sciences, 2020 - Elsevier
The present pandemic of SARS-CoV-2 has been a tough task for the whole world to deal
with. With the absence of specific drugs or vaccines against SARS-CoV-2, the situation is …

[HTML][HTML] Antivirals with common targets against highly pathogenic viruses

L Lu, S Su, H Yang, S Jiang - Cell, 2021 - cell.com
Historically, emerging viruses appear constantly and have cost millions of human lives.
Currently, climate change and intense globalization have created favorable conditions for …

Ebola

H Feldmann, A Sprecher… - New England Journal of …, 2020 - Mass Medical Soc
Ebola | New England Journal of Medicine Skip to main content The New England Journal of
Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical Medicine …

A promising antiviral candidate drug for the COVID-19 pandemic: A mini-review of remdesivir

C Liang, L Tian, Y Liu, N Hui, G Qiao, H Li, Z Shi… - European journal of …, 2020 - Elsevier
Abstract Remdesivir (GS-5734), a viral RNA-dependent RNA polymerase (RdRP) inhibitor
that can be used to treat a variety of RNA virus infections, is expected to be an effective …

[HTML][HTML] Recent advances in carbon quantum dots for virus detection, as well as inhibition and treatment of viral infection

Y Xue, C Liu, G Andrews, J Wang, Y Ge - Nano Convergence, 2022 - Springer
In the last decade, carbon quantum dots (CQDs), as a novel class of carbon-based
nanomaterials, have received increasing attention due to their distinct properties. CQDs are …

[HTML][HTML] Drug discovery strategies for SARS-CoV-2

ZA Shyr, K Gorshkov, CZ Chen, W Zheng - Journal of Pharmacology and …, 2020 - ASPET
Coronavirus disease 2019 (COVID-19) is a novel disease caused by the severe acute
respiratory syndrome coronavirus (SARS-CoV)-2 virus that was first detected in December of …