Hear and now: Ongoing clinical trials to prevent drug-induced hearing loss

J Lee, K Fernandez… - Annual Review of …, 2024 - annualreviews.org
Each year over half a million people experience permanent hearing loss caused by
treatment with therapeutic drugs with ototoxic side effects. There is a major unmet clinical …

Progress on mechanisms of age-related hearing loss

W Yang, X Zhao, R Chai, J Fan - Frontiers in neuroscience, 2023 - frontiersin.org
Age-related hearing loss, or presbycusis, is a common cause of hearing loss in elderly
people worldwide. It typically presents as progressive, irreversible, and usually affects the …

Natural Multifunctional Silk Microcarriers for Noise‐Induced Hearing Loss Therapy

H Zhang, H Chen, L Lu, H Wang, Y Zhao… - Advanced …, 2024 - Wiley Online Library
Noise‐induced hearing loss (NIHL) is a common outcome of excessive reactive oxygen
species in the cochlea, and the targeted delivery of antioxidants to the inner ear is a …

Characteristics of brain glucose metabolism and metabolic connectivity in noise-induced hearing loss

S Shin, HY Nam - Scientific Reports, 2023 - nature.com
The purpose of this study was to evaluate the differences in cerebral glucose metabolism
and metabolic connectivity between noise-induced hearing loss (NIHL) subjects and normal …

Evaluation of Noise Levels in a University Dental Clinic

M Antoniadou, P Tziovara, S Konstantopoulou - Applied Sciences, 2023 - mdpi.com
Noise levels in a dental office can be produced by different specialty instruments. Exposure
to high levels of noise (unwanted sounds) may cause auditory and non-auditory health …

Fatty acid binding protein type 7 deficiency preserves auditory function in noise-exposed mice

J Suzuki, T Hemmi, M Maekawa, M Watanabe… - Scientific Reports, 2023 - nature.com
Fatty acid-binding protein 7 (FABP7) is vital for uptake and trafficking of fatty acids in the
nervous system. To investigate the involvement of FABP7 in noise-induced hearing loss …

Comparative transcriptome profiling reveals RNA splicing alterations and biological function in patients exposed to occupational noise

JW Chen, JJ Shao, SF Zhao, PH Lu, SY Li… - … Science and Pollution …, 2023 - Springer
Genetic factors play an important role in susceptibility to noise-induced hearing loss (NIHL).
Alternative splicing (AS) is an essential mechanism affecting gene expression associated …

2D Catalytic Niobium Carbide MXenzyme for Ameliorating Noise‐Induced Hearing Loss

B Xu, Q Jiang, Y Huang, K Xu, W Feng… - Advanced Functional …, 2024 - Wiley Online Library
Noise‐induced hearing loss (NIHL), a prevalent sensory disability affecting a majority of the
global population, is dominantly induced by mitochondrial dysfunction and oxidative stress …

Effects of Astragaloside IV on Hearing, Inflammatory Factors, and Intestinal Flora in Mice Exposed to Noise

J Li, J Yang, Y Xia, J Wang, Y Xia - Metabolites, 2024 - mdpi.com
Long-term exposure to noise can cause irreversible hearing loss. Considering that there is
no effective drug treatment, it is important to seek preventive treatment for noise-induced …

Tinnitus prevalence, associated characteristics, and related healthcare use in the United States: a population-level analysis

S Batts, KM Stankovic - The Lancet Regional Health–Americas, 2024 - thelancet.com
Background Tinnitus is a potentially disabling condition with few treatments. We examined
the prevalence and characteristics of tinnitus among demographic groups in the United …