Immune and inflammatory mechanisms in hypertension

TJ Guzik, R Nosalski, P Maffia… - Nature Reviews …, 2024 - nature.com
Hypertension is a global health problem, with> 1.3 billion individuals with high blood
pressure worldwide. In this Review, we present an inflammatory paradigm for hypertension …

Monocyte‐related cytokines/chemokines in cerebral ischemic stroke

M Bai, R Sun, B Cao, J Feng… - CNS Neuroscience & …, 2023 - Wiley Online Library
Aims Ischemic stroke is one of the leading causes of death worldwide and the most common
cause of disability in Western countries. Multiple mechanisms contribute to the development …

Decreased oocyte quality in patients with endometriosis is closely related to abnormal granulosa cells

W Fan, Z Yuan, M Li, Y Zhang, F Nan - Frontiers in Endocrinology, 2023 - frontiersin.org
Infertility and menstrual abnormalities in endometriosis patients are frequently caused by
aberrant follicular growth or a reduced ovarian reserve. Endometriosis typically does not …

[HTML][HTML] Role of MCP-1/CCR2 axis in renal fibrosis: Mechanisms and therapeutic targeting

S He, L Yao, J Li - Medicine, 2023 - journals.lww.com
Renal fibrosis is a common pathological manifestation in various chronic kidney diseases.
Inflammation plays a central role in renal fibrosis development. Owing to their significant …

HIV-associated cardiovascular disease pathogenesis: an emerging understanding through imaging and immunology

JA Hudson, RA Ferrand, SN Gitau… - Circulation …, 2024 - Am Heart Assoc
Cardiac abnormalities were identified early in the epidemic of AIDS, predating the isolation
and characterization of the etiologic agent, HIV. Several decades later, the causation and …

Trafficking and effect of released DNA on cGAS-STING signaling pathway and cardiovascular disease

Z Zhou, C Ou-Yang, Q Chen, Z Ren, X Guo… - Frontiers in …, 2023 - frontiersin.org
Evidence from clinical research and animal studies indicates that inflammation is an
important factor in the occurrence and development of cardiovascular disease (CVD) …

Low-intensity pulsed ultrasound of different intensities differently affects myocardial ischemia/reperfusion injury by modulating cardiac oxidative stress and …

Q Cao, L Liu, Y Hu, S Cao, T Tan, X Huang… - Frontiers in …, 2023 - frontiersin.org
Introduction The prevalence of ischemic heart disease has reached pandemic levels
worldwide. Early revascularization is currently the most effective therapy for ischemic heart …

Role of MCP-1 as an inflammatory biomarker in nephropathy

Y Liu, K Xu, Y Xiang, B Ma, H Li, Y Li, Y Shi… - Frontiers in …, 2024 - frontiersin.org
The Monocyte chemoattractant protein-1 (MCP-1), also referred to as chemokine ligand 2
(CCL2), belongs to the extensive chemokine family and serves as a crucial mediator of …

miRNAs epigenetic tuning of wall remodeling in the early phase after myocardial infarction: A Novel epidrug approach

F Salvatori, E D'Aversa, ML Serino, AV Singh… - International Journal of …, 2023 - mdpi.com
Myocardial infarction (MI) is one of the leading causes of death in Western countries. An
early diagnosis decreases subsequent severe complications such as wall remodeling or …

Micro-and Macrovascular Effects of Inflammation in Peripheral Artery Disease—Pathophysiology and Translational Therapeutic Approaches

M Poledniczek, C Neumayer, CW Kopp, O Schlager… - Biomedicines, 2023 - mdpi.com
Inflammation has a critical role in the development and progression of atherosclerosis. On
the molecular level, inflammatory pathways negatively impact endothelial barrier properties …