An update of epigenetic drugs for the treatment of cancers and brain diseases: a comprehensive review

Z Sahafnejad, S Ramazi, A Allahverdi - Genes, 2023 - mdpi.com
Epigenetics has long been recognized as a significant field in biology and is defined as the
investigation of any alteration in gene expression patterns that is not attributed to changes in …

[HTML][HTML] A systematic review of computational approaches to understand cancer biology for informed drug repurposing

F Ahmed, A Samantasinghar, AM Soomro, S Kim… - Journal of Biomedical …, 2023 - Elsevier
Cancer is the second leading cause of death globally, trailing only heart disease. In the
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …

[HTML][HTML] Single nucleotide polymorphisms (SNPs) in prostate cancer: its implications in diagnostics and therapeutics

KS Allemailem, A Almatroudi, F Alrumaihi… - American journal of …, 2021 - ncbi.nlm.nih.gov
Prostate cancer is one of the most frequently diagnosed malignancies in developed
countries and approximately 248,530 new cases of prostate cancer are likely to be …

Genome-wide association study for alcohol-related cirrhosis identifies risk loci in MARC1 and HNRNPUL1

H Innes, S Buch, S Hutchinson, IN Guha, JR Morling… - Gastroenterology, 2020 - Elsevier
Background and Aims Little is known about genetic factors that affect development of
alcohol-related cirrhosis. We performed a genome-wide association study (GWAS) of …

RNA recording in single bacterial cells using reprogrammed tracrRNAs

C Jiao, C Reckstadt, F König, C Homberger, J Yu… - Nature …, 2023 - nature.com
Capturing an individual cell's transcriptional history is a challenge exacerbated by the
functional heterogeneity of cellular communities. Here, we leverage reprogrammed …

[HTML][HTML] Significance of the estrogen hormone and single nucleotide polymorphisms in the progression of breast cancer among female

M Alwan, F Afzaljavan - Archives of Razi Institute, 2022 - ncbi.nlm.nih.gov
Breast cancer is one of the most frequent types of malignancies among women and is
internationally recognized as the main reason for cancer-caused mortality. Most breast …

DNA-coded metal nano-fluorophores: Preparation, properties and applications in biosensing and bioimaging

F Xu, T Qing, Z Qing - Nano Today, 2021 - Elsevier
Fluorescent metal nanoclusters (MNCs), composed of a few to hundreds of noble metal
atoms, are a type of sub-nanometer scale transitional material between atoms and …

Mechanisms by which probiotic bacteria attenuate the risk of hepatocellular carcinoma

WPDW Thilakarathna, HPV Rupasinghe… - International Journal of …, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the second
leading cause of cancer-related deaths worldwide. Chronic infections with hepatitis B virus …

DNA methylation in genes associated with the evolution of ageing and disease: A critical review

MT Mc Auley - Ageing Research Reviews, 2021 - Elsevier
Ageing is characterised by a physical decline in biological functioning which results in a
progressive risk of mortality with time. As a biological phenomenon, it is underpinned by the …

Analysis of genetic biomarkers, polymorphisms in ADME-related genes and their impact on pharmacotherapy for prostate cancer

K Rehman, Z Iqbal, D Zhiqin, H Ayub, N Saba… - Cancer Cell …, 2023 - Springer
Prostate cancer (PCa) is a non-cutaneous malignancy in males with wide variation in
incidence rates across the globe. It is the second most reported cause of cancer death. Its …