Scopoletin, also known as 6-methoxy-7 hydroxycoumarin, is one of the naturally occurring
coumarin commonly found in many edible plants and plays an important role in human …

Natural and synthetic coumarins have been extensively described in the literature as
effective drugs with several pharmacological activities. Many valuable publications have …

Diabetic neuropathy is a frequent complication of diabetes. Symptoms include neuropathic
pain and sensory alterations—no effective treatments are currently available. This work …

Chromones are a group of natural substances with a diversity of biological activities. Herein
we assessed the pharmacological potential of three chromones (1, 2 and 3) isolated from …

Despite advancements in the areas of omics and chemoinformatics, potent novel
biotherapeutic molecules with new modes of actions are needed for leishmaniasis. The …

Introduction Degenerative cervical myelopathy (DCM) is a common and disabling condition
of symptomatic cervical spinal cord compression secondary to degenerative changes in …

It is now well recognized that the normal cellular response in mammalian cells is critically
regulated by the cyclic-AMP (cAMP) pathway through the appropriate balance of adenylyl …

This current study presents the phytochemical analysis of Croton velutinus, describing
phenylpropanoids obtained from this species. The fractionation of the roots hexane extract …

Ethnopharmacological relevance Physalis angulata is an herb found in tropical and
subtropical regions of the world; it is widely applied in popular medicine due to the …

The compound (E)-2-cyano-N, 3-diphenylacrylamide (JMPR-01) was structurally developed
using bioisosteric modifications of a hybrid prototype as formed from fragments of …