The role of the medial geniculate body of the thalamus in the pathophysiology of tinnitus and implications for treatment

F Almasabi, MLF Janssen, J Devos, M Moerel… - Brain Research, 2022 - Elsevier
Tinnitus is an auditory sensation in the absence of actual external stimulation. Different
clinical interventions are used in tinnitus treatment, but only few patients respond to …

An implementation science systematic review of neurophysiological evidence indicates the tinnitus core network as a therapeutic target

LJ Burton-Harris, PJ Sanders… - Frontiers in Audiology …, 2023 - frontiersin.org
Identifying and implementing an effective tinnitus treatment has been a challenge. Despite
efforts over many decades, there is no definitive cure for tinnitus yet. Implementation science …

Decreased modulation of population correlations in auditory cortex is associated with decreased auditory detection performance in old mice

K Shilling-Scrivo, J Mittelstadt… - Journal of …, 2022 - Soc Neuroscience
Age-related hearing loss (presbycusis) affects one-third of the world's population. One
hallmark of presbycusis is difficulty hearing in noisy environments. Presbycusis can be …

Application and prospect of quasi-targeted metabolomics in age-related hearing loss

C Wang, J Qiu, G Li, J Wang, D Liu, L Chen, X Song… - Hearing Research, 2022 - Elsevier
Age-related hearing loss (ARHL) is a common sensory deficit in the elderly, which seriously
affects physical and mental health. Therefore, understanding its underlying molecular …

A Developmental Switch in Cholinergic Mechanisms of Modulation in the Medial Nucleus of the Trapezoid Body

SR Weimann, C Zhang, RM Burger - Journal of Neuroscience, 2024 - Soc Neuroscience
The medial nucleus of the trapezoid body (MNTB) has been intensively investigated as a
primary source of inhibition in brainstem auditory circuitry. MNTB-derived inhibition plays a …

Noise-induced hearing loss alters potassium-chloride cotransporter KCC2 and GABA inhibition in the auditory centers

V Parameshwarappa, MI Siponen, I Watabe… - Scientific Reports, 2024 - nature.com
Homeostatic plasticity, the ability of neurons to maintain their averaged activity constant
around a set point value, is thought to account for the central hyperactivity after hearing loss …

Cholinergic modulation in the vertebrate auditory pathway

C Zhang, RM Burger - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Acetylcholine (ACh) is a prevalent neurotransmitter throughout the nervous system. In the
brain, ACh is widely regarded as a potent neuromodulator. In neurons, ACh signals are …

Research progress of the inferior colliculus: from Neuron, neural circuit to auditory disease

M Liu, Y Wang, L Jiang, X Zhang, C Wang, T Zhang - Brain Research, 2024 - Elsevier
The auditory midbrain, also known as the inferior colliculus (IC), serves as a crucial hub in
the auditory pathway. Comprising diverse cell types, the IC plays a pivotal role in various …

The distribution pattern of M2 and Adrenergicα2 receptors on inferior colliculi in male newborns of diabetic rats

M Ghenaatgar-Kasbi, G Sazegar, S Fallahnezhad… - Neuroscience …, 2022 - Elsevier
Aims Despite the high prevalence of diabetes in the world, its possible effects throughut
pregnancy on neonatal auditory nervous system development are still unknown. In the …

Aging effects on the neural representation and perception of consonant transition cues

AA Poe, H Karawani, S Anderson - Hearing Research, 2024 - Elsevier
Older listeners have difficulty processing temporal cues that are important for word
discrimination, and deficient processing may limit their ability to benefit from these cues …