[HTML][HTML] SARS-CoV-2 infection and dysregulation of nuclear factor erythroid-2-related factor 2 (Nrf2) pathway

RS Hamad, HM Al-Kuraishy, A Alexiou… - Cell Stress and …, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic caused by a novel
severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) leading to pulmonary and …

Statin use in relation to COVID-19 and other respiratory infections: Muscle and other considerations

BA Golomb, JH Han, PH Langsjoen… - Journal of Clinical …, 2023 - mdpi.com
Statins have been widely advocated for use in COVID-19 based on large favorable
observational associations buttressed by theoretical expected benefits. However, past …

[HTML][HTML] The evolving role of cholesteryl ester transfer protein inhibition beyond cardiovascular disease

N Mehta, K Dangas, M Ditmarsch, PCN Rensen… - Pharmacological …, 2023 - Elsevier
The main role of cholesteryl ester transfer protein (CETP) is the transfer of cholesteryl esters
and triglycerides between high-density lipoprotein (HDL) particles and triglyceride-rich …

SARS-CoV-2 nucleocapsid protein promotes TMAO-induced NLRP3 inflammasome activation by SCAP–SREBP signaling pathway

MH Liu, XL Lin, LL Xiao - Tissue and Cell, 2024 - Elsevier
Highlights•SARS-CoV-2 nucleocapsid protein amplified the Trimethylamine N-oxide-
induced NLRP3 inflammasome activation and lipogenesis.•TMAO‐induced TMAO-induced …

Association between lipid profile and clinical outcomes in COVID-19 patients

LA Ochoa-Ramírez, AK De la Herrán Arita… - Scientific Reports, 2024 - nature.com
High-density lipoprotein cholesterol (HDL-c) removes cholesterol, an essential component
in lipid rafts, and this cholesterol removal can regulate protein attachment to lipid rafts …

The anti-inflammatory properties of vinpocetine mediates its therapeutic potential in management of atherosclerosis

AA Alshehri, HM Al-Kuraishy, AI Al-Gareeb… - Journal of …, 2024 - Springer
Atherosclerosis (AS) formation is enhanced by different mechanisms including cytokine
generation, vascular smooth muscle cell proliferation, and migration. One of the recent …

Thapsigargin and Tunicamycin Block SARS-CoV-2 Entry into Host Cells via Differential Modulation of Unfolded Protein Response (UPR), AKT Signaling, and …

A Al Otaibi, S Al Shaikh Mubarak, F Al Hejji… - Cells, 2024 - mdpi.com
Background: SARS-Co-V2 infection can induce ER stress-associated activation of unfolded
protein response (UPR) in host cells, which may contribute to the pathogenesis of COVID …

Longitudinal NMR-Based Metabolomics Study Reveals How Hospitalized COVID-19 Patients Recover: Evidence of Dyslipidemia and Energy Metabolism …

L Ansone, V Rovite, M Brīvība, L Jagare… - International Journal of …, 2024 - mdpi.com
Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), can manifest as long-
term symptoms in multiple organ systems, including respiratory, cardiovascular …

Serum Clusterin Concentration and Its Glycosylation Changes as Potential New Diagnostic Markers of SARS-CoV-2 Infection and Recovery Process

K Sołkiewicz, I Kokot, M Kacperczyk… - International Journal of …, 2024 - mdpi.com
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. Glycoprotein clusterin
(CLU) has many functions such as phagocyte recruitment, complement system inhibition …

[HTML][HTML] Pathogenic mechanisms of cardiovascular damage in COVID-19

HH Shao, RX Yin - Molecular Medicine, 2024 - ncbi.nlm.nih.gov
Background COVID-19 is a new infectious disease caused by the severe acute respiratory
syndrome coronavirus 2 (SARS CoV-2). Since the outbreak in December 2019, it has …