Resveratrol regulates inflammation and improves oxidative stress via Nrf2 signaling pathway: Therapeutic and biotechnological prospects
SH Shahcheraghi, F Salemi, S Small… - Phytotherapy …, 2023 - Wiley Online Library
Usually, in aerobic metabolism, natural materials including nucleic acids, proteins, and lipids
can experience auxiliary injury by oxidative responses. This damage produced by reactive …
can experience auxiliary injury by oxidative responses. This damage produced by reactive …
Targeting VCAM-1: a therapeutic opportunity for vascular damage
MF Troncoso, MC Díaz-Vesga… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The vascular cell adhesion molecule (VCAM-1) is a transmembrane
sialoglycoprotein detected in activated endothelial and vascular smooth muscle cells …
sialoglycoprotein detected in activated endothelial and vascular smooth muscle cells …
[HTML][HTML] CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization
YL Zhang, J Bai, WJ Yu, QY Lin, HH Li - Journal of Advanced Research, 2024 - Elsevier
Introduction Leukocyte infiltration is an early event during cardiac remodeling frequently
leading to heart failure (HF). Integrins mediate leukocyte infiltration during inflammation …
leading to heart failure (HF). Integrins mediate leukocyte infiltration during inflammation …
Integrin CD11b contributes to hypertension and vascular dysfunction through mediating macrophage adhesion and migration
QY Lin, J Bai, YL Zhang, HH Li - Hypertension, 2023 - Am Heart Assoc
Background: Leukocyte adhesion to endothelium is an early inflammatory response and is
mainly controlled by the β2-integrins. However, the role of integrin CD11b/CD18 in the …
mainly controlled by the β2-integrins. However, the role of integrin CD11b/CD18 in the …
Blocking VCAM-1 ameliorates hypertensive cardiac remodeling by impeding macrophage infiltration
ZY Qiu, WJ Yu, J Bai, QY Lin - Frontiers in Pharmacology, 2022 - frontiersin.org
Cardiac remodeling is an important mechanism of heart failure, which frequently results from
leukocyte infiltration. Vascular cellular adhesion molecule-1 (VCAM-1) plays a critical role in …
leukocyte infiltration. Vascular cellular adhesion molecule-1 (VCAM-1) plays a critical role in …
[HTML][HTML] Myeloid ACE2 protects against septic hypotension and vascular dysfunction through Ang-(1–7)-Mas-mediated macrophage polarization
JX Li, X Xiao, F Teng, HH Li - Redox Biology, 2024 - Elsevier
Abstract Angiotensin converting enzyme 2 (ACE2) is a new identified member of the renin-
angiotensin-aldosterone system (RAAS) that cleaves angiotensin II (Ang II) to Ang (1–7) …
angiotensin-aldosterone system (RAAS) that cleaves angiotensin II (Ang II) to Ang (1–7) …
Serum VCAM‐1 and ICAM‐1 measurement assists for MACE risk estimation in ST‐segment elevation myocardial infarction patients
J Yu, Y Liu, W Peng, Z Xu - Journal of Clinical Laboratory …, 2022 - Wiley Online Library
Background Vascular cell adhesion molecule‐1 (VCAM‐1) and intercellular adhesion
molecule‐1 (ICAM‐1) modulate atherosclerosis by promoting leukocyte infiltration …
molecule‐1 (ICAM‐1) modulate atherosclerosis by promoting leukocyte infiltration …
[HTML][HTML] Sacubitril/valsartan attenuates myocardial inflammation, hypertrophy, and fibrosis in rats with heart failure with preserved ejection fraction
YJ Shi, CG Yang, WB Qiao, YC Liu, SY Liu… - European Journal of …, 2023 - Elsevier
Heart failure with preserved ejection fraction (HFpEF) represents a multifaceted syndrome
related to complex pathologic mechanisms. Sacubitril/valsartan (Sac/val) has demonstrated …
related to complex pathologic mechanisms. Sacubitril/valsartan (Sac/val) has demonstrated …
A rat model of metabolic syndrome-related heart failure with preserved ejection fraction phenotype: pathological alterations and possible molecular mechanisms
Y Shi, C Liu, C Yang, W Qiao, Y Liu, S Liu… - Frontiers in …, 2023 - frontiersin.org
Background Heart failure with preserved ejection fraction (HFpEF) represents a syndrome
involving multiple pathophysiologic disorders and clinical phenotypes. This complexity …
involving multiple pathophysiologic disorders and clinical phenotypes. This complexity …
Ginaton reduces M1-polarized macrophages in hypertensive cardiac remodeling via NF-κB signaling
J Wang, E Cai, X An, J Wang - Frontiers in Pharmacology, 2023 - frontiersin.org
Introduction: Macrophages play a critical role in cardiac remodeling, and dysregulated
macrophage polarization between the proinflammatory M1 and anti-inflammatory M2 …
macrophage polarization between the proinflammatory M1 and anti-inflammatory M2 …