The outbreak of the coronavirus disease 2019 (COVID-19), caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become an evolving global …

Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …

Cytokine storm syndromes (CSSs) are potentially fatal hyperinflammatory states that share
the underpinnings of persistent immune cell activation and uninhibited cytokine production …

Patients with familial hypercholesterolemia (FH) are likely at increased risk for COVID-19
complications in the acute phase of the infection, and for a long time thereafter. Because in …

Cytokine storm is a severe immune response that can be triggered by the coronavirus SARS-
CoV-2 infection in susceptible patients, and, in the severe form of the COVID-19 disease, it is …

Severe cases of SARS-CoV-2 infection are characterized by an immune response that leads
to the overproduction of pro-inflammatory cytokines, resulting in lung damage …

Background: Following its initial description in December 2019 in Wuhan, China,
coronavirus-2 (COVID‐19) has rapidly progressed into a worldwide pandemic, affecting …

Abstract Severely ill COVID–19 (Corona Virus Disease of 2019) patients have a
hyperinflammatory condition with a high concentration of pro-inflammatory cytokines termed …

Computational drug repositioning aims at ranking and selecting existing drugs for novel
diseases or novel use in old diseases. In silico drug screening has the potential for speeding …

Severe forms of the Coronavirus disease 2019 (COVID-19) are characterized by an
enhanced inflammatory syndrome called “cytokine storm” that produces an aberrant release …