This narrative review presents an overview of current knowledge on fertility and reproductive
hormone changes in aging men, the factors driving and modulating these changes, their …

In this narrative review, we discuss the evidence about the controversy about the
cardiovascular effects of endogenous and exogenous testosterone in men. Prospective …

Background Low total testosterone (TT) and sex hormone-binding globulin (SHBG)
concentrations have been associated with the metabolic syndrome (MetS) in men, but the …

Context: Polycystic ovary syndrome (PCOS) is a heterogeneous disease with many different
aspects, including hyperandrogenism and metabolic disturbances. Clinical phenotypes …

Objective It is yet unknown to which degree young subfertile men present with signs of
hypogonadism and whether low testosterone concentration, like in older men, is associated …

This study analysed the associations of sex steroids with fat-free mass (FFM) and handgrip
strength in 641 Chinese boys. Serum total testosterone (TT) and oestradiol were measured …

This narrative review summarizes key points of the pathogenesis and diagnosis of the
ageing-related decline of testosterone (T) in men. The condition is commonly termed late …

All forms of hypogonadism–primary, secondary and late-onset–require testosterone
substitution. The indication is given when the patient presents with symptoms of androgen …

To make the diagnosis of hypogonadism in an ageing man, in absence of rare organic
cause often referred to as functional or late onset hypogonadism (LOH), he should present …

Age and female sex have repeatedly been identified as gallstone determinants but the
underlying mechanisms are not clarified. The objectives of this study were to determine if …