[HTML][HTML] The effects of intermittent fasting on brain and cognitive function
The importance of diet and the gut-brain axis for brain health and cognitive function is
increasingly acknowledged. Dietary interventions are tested for their potential to prevent …
increasingly acknowledged. Dietary interventions are tested for their potential to prevent …
The role of antioxidants in the interplay between oxidative stress and senescence
Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …
Daily caloric restriction limits tumor growth more effectively than caloric cycling regardless of dietary composition
LCD Pomatto-Watson, M Bodogai, O Bosompra… - Nature …, 2021 - nature.com
Cancer incidence increases with age and is a leading cause of death. Caloric restriction
(CR) confers benefits on health and survival and delays cancer. However, due to CR's …
(CR) confers benefits on health and survival and delays cancer. However, due to CR's …
Age-related mitochondrial dysfunction as a key factor in COVID-19 disease
DJM Fernández-Ayala, P Navas… - Experimental gerontology, 2020 - Elsevier
SARS-CoV-2 causes a severe pneumonia (COVID-19) that affects essentially elderly
people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense …
people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense …
Mechanisms of lifespan regulation by calorie restriction and intermittent fasting in model organisms
Genetic and pharmacological interventions have successfully extended healthspan and
lifespan in animals, but their genetic interventions are not appropriate options for human …
lifespan in animals, but their genetic interventions are not appropriate options for human …
Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults
CR Martens, MJ Rossman, MR Mazzo, LR Jankowski… - Geroscience, 2020 - Springer
Chronic calorie restriction (CR) improves cardiovascular function and several other
physiological markers of healthspan. However, CR is impractical in non-obese older …
physiological markers of healthspan. However, CR is impractical in non-obese older …
Alternate day fasting improves physiological and molecular markers of aging in healthy, non-obese humans
Caloric restriction and intermittent fasting are known to prolong life-and healthspan in model
organisms, while their effects on humans are less well studied. In a randomized controlled …
organisms, while their effects on humans are less well studied. In a randomized controlled …
Where metabolism meets senescence: focus on endothelial cells
Despite the decline in their proliferative potential, senescent cells display a high metabolic
activity. Senescent cells have been shown to acquire a more glycolytic state even in …
activity. Senescent cells have been shown to acquire a more glycolytic state even in …
Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis, and expression of longevity gene Klotho
GP Dias, T Murphy, D Stangl, S Ahmet, B Morisse… - Molecular …, 2021 - nature.com
Daily calorie restriction (CR) and intermittent fasting (IF) enhance longevity and cognition but
the effects and mechanisms that differentiate these two paradigms are unknown. We …
the effects and mechanisms that differentiate these two paradigms are unknown. We …
Intermittent fasting: from calories to time restriction
E Duregon, LCDD Pomatto-Watson, M Bernier… - Geroscience, 2021 - Springer
The global human population has recently experienced an increase in life expectancy with a
mounting concern about the steady rise in the incidence of age-associated chronic diseases …
mounting concern about the steady rise in the incidence of age-associated chronic diseases …