Emerging new evidence highlights the importance of prolonged daily fasting periods for the
health and survival benefits of calorie restriction (CR) and time-restricted feeding (TRF) in …

Abstract Purpose of Review This article reviews the current literature on dietary
interventions, including time-restricted eating (TRE), intermittent fasting (IF), and fasting …

The identification of genes and interventions that slow or reverse aging is hampered by the
lack of non-invasive metrics that can predict the life expectancy of pre-clinical models. Frailty …

Intermittent fasting (IF), time-restricted eating (TRE) and fasting-mimicking diets (FMD) are
gaining popularity as weight loss programs. As such, the timing and frequency of meals …

The impact of chronic caloric restriction (CR) on health and survival is complex with poorly
understood underlying molecular mechanisms. A recent study in mice addressing the diets …

Cardiovascular disease (CVD) is the leading cause of death in many developed countries
and remains one of the major diseases strongly affected by the diet. Nutrition can affect CVD …

Overnutrition is a risk factor for various human diseases, including neurodegenerative
diseases, metabolic disorders, and cancers. Therefore, targeting overnutrition represents a …

In recent years a revival of interest has emerged in the health benefits of intermittent fasting
and long-term fasting, as well as of other related nutritional strategies. In addition to meal …

All biological processes, living organisms, and ecosystems have evolved with the Sun that
confers a 24-hour periodicity to life on Earth. Circadian rhythms arose from evolutionary …

Dysfunctional mitochondrial quality control (MQC) is implicated in the pathogenesis of
Parkinson's disease (PD). The improper selection of mitochondria for mitophagy increases …