SNRPD1 inhibition suppresses the proliferation of hepatocellular carcinoma and promotes autophagy through the PI3K/AKT/mTOR/4EBP1 pathway

H Wang, M Chen, C Yang, H Hu, Y Jiang… - Archives of Biochemistry …, 2023 - Elsevier
Abstract Background Small nuclear ribonucleoprotein Sm D1 (SNRPD1) has been reported
as an oncogene in some solid cancers. Our previous study suggested that SNRPD1 has …

Alternative mRNA Splicing and Polyadenylation Events are Synchronous with Podocyte Injury and Slit Diaphragm Dysregulation in Glomerular Disease Models

MK Das, A Webb, M Yarram, C Reilly, C Bryant… - bioRxiv, 2024 - biorxiv.org
Background: Glomerular disease, often characterized by podocyte injury and proteinuria,
can lead to chronic kidney disease and end stage kidney disease. We hypothesized that the …