Trends in the use of pharmacotherapies for acute myocardial infarction among physicians who design and/or implement randomized trials versus physicians in routine …

JR Kizer, CP Cannon, CH McCabe, HS Mueller… - American heart …, 1999 - Elsevier
Background Although studies have documented that randomized, controlled trials (RCTs)
have a measurable influence on clinical practice, investigators have uncovered important …

Is aspirin ″the weakest link” in cardiovascular prophylaxis? The surprising lack of evidence supporting the use of aspirin for cardiovascular disease

JGF Cleland - Progress in cardiovascular diseases, 2002 - Elsevier
It is currently fashionable to prescribe aspirin, long-term to people with or at high risk of
vascular events due to atherosclerosis. There is a moderately conclusive evidence for a …

Rationale, design and organization of the Second Chinese Cardiac Study (CCS-2): a randomized trial of clopidogrel plus aspirin, and of metoprolol, among patients …

ZM Chen… - European Journal of …, 2000 - academic.oup.com
Assessing combined anti-platelet therapy in suspected acute myocardial infarction Aspirin
has been shown to be effective in the emergency treatment of acute myocardial infarction. It …

临床医学模式转变—从经验医学到循证医学

胡大一, 顼志敏 - 中国实用内科杂志, 1998 - cqvip.com
近年来, 临床研究与实践进入了一个全新的时代, 临床医学模式发生了巨大转变,
即从经验医学到循证医学. 循证医学是近年兴起的一门学科, 是医学治疗学的决策指南和发展 …

Changes in vasoconstrictive hormones, natriuretic peptides, and left ventricular remodeling soon after anterior myocardial infarction

M White, JL Rouleau, C Hall, M Arnold, F Harel… - American heart …, 2001 - Elsevier
Objective Our purpose was to study the changes in vasoconstrictive neurohormones, N-
terminal proatrial natriuretic peptide (Nt-proANP), and brain natriuretic peptide (BNP) and …

First‐dose hypotension after angiotensin‐converting enzyme (ACE) inhibitors in chronic heart failure: a comparison of enalapril and perindopril

J Vítovec, J Špinar… - European Journal of …, 2000 - Wiley Online Library
Background: First‐dose hypotension refers to an observed reduction in blood pressure after
the administration of the first dose of ACE inhibitors in patients with congestive heart failure …

Treatment for acute myocardial infarction: overview of randomized clinical trials

S Yusuf, S Anand, A Avezum Jr, M Flather… - European heart …, 1996 - academic.oup.com
This review summarizes the results of several pharmacological interventions that have been
evaluated in the management of acute myocardial infarction. Of these, thrombolytic therapy …

A decade of clinical trial developments in postmyocardial infarction, congestive heart failure, and sustained ventricular tachyarrhythmia patients: from CAST to AVID …

GV NACCARELLLI, DL Wolbrette… - Journal of …, 1998 - Wiley Online Library
A Decade of Clinical Trials. Multiple trials using antiarrhythmic drugs, pharmacologic
therapy, and implantable cardioverter defibrillators have been performed in an attempt to …

Differential antiplatelet effects of angiotensin converting enzyme inhibitors: comparison of ex vivo platelet aggregation in cardiovascular patients with ramipril, captopril …

D Skowasch, A Viktor, M Schneider-Schmitt… - Clinical research in …, 2006 - Springer
Background Increasing evidence suggests that angiotensin converting enzyme (ACE)
inhibitors exert antithrombotic effects. Based on the assumption of differential effects of …

Impact of renin-angiotensin system blockade on the prognosis of acute coronary syndrome based on left ventricular ejection fraction

S Raposeiras-Roubín, E Abu-Assi… - Revista Española de …, 2020 - Elsevier
Introduction and objectives For patients with acute coronary syndrome (ACS) treated with
percutaneous coronary intervention (PCI), it is unclear whether angiotensin-converting …