Hypertension, a leading cause of morbidity and mortality, accounts for 25–49% of all strokes.
Randomized placebo‐controlled trials primarily with diuretics and β‐blockers administered …

Meta-analysis is commonly used in reviews of the effectiveness of medical technologies, but
this approach has not been used in direct support of guidelines development groups. This …

ACE inhibitors have been shown to be effective in reducing the morbidity and mortality of
patients with left ventricular systolic dysfunction, but their application to clinical practice in …

En 1987 se publicaron los resultados del estudio Consensus, que demostró que un
inhibidor de la enzima de conversión de la angiotensina (IECA), el enalapril, era capaz de …

Over 80 per cent of the global disease burden occurs in developing countries. Yet the
proportion of research conducted in these countries is less than 10 per cent of the global …

Angiotensin-converting enzyme inhibitors (ACE-I) were initially developed as therapeutic
agents targeted for the treatment of hypertension. Since the initial application of these …

Left ventricular remodeling is the major mechanism leading to cardiac enlargement, failure,
and death after myocardial infarction. It is associated with early disruption of collagen matrix …

Background Many trials have proved the benefits of early systematic treatment with
angiotensin-converting enzyme inhibitors in patients with acute myocardial infarction (AMI) …

Статья была опубликована в издании «Кардиология»(2008, 11) пию каптоприлом (до
150 мг/сут) начинали между 3-ми и 16-ми сутками ОИМ (в среднем на 11-й день) …

Aims Many clinical trials conducted in the 1970s and early 1980s have shown that the long-
term use of beta-blockers after an acute myocardial infarction significantly reduces mortality …