[HTML][HTML] Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19

C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …

Crosstalk between COVID-19 infection and kidney diseases: a review on the metabolomic approaches

R Murali, UR Wanjari, AG Mukherjee… - Vaccines, 2023 - mdpi.com
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-
19, a respiratory disorder. Various organ injuries have been reported in response to this …

Gastrointestinal symptoms of long COVID-19 related to the ectopic colonization of specific bacteria that move between the upper and lower alimentary tract and …

D Zhang, S Weng, C Xia, Y Ren, Z Liu, Y Xu, X Yang… - BMC medicine, 2023 - Springer
Background Since the coronavirus disease 2019 (COVID-19) outbreak, many COVID-19
variants have emerged, causing several waves of pandemics and many infections. Long …

Label-free SERS for rapid differentiation of SARS-CoV-2-induced serum metabolic profiles in non-hospitalized adults

M Chisanga, H Williams, D Boudreau… - Analytical …, 2023 - ACS Publications
COVID-19 represents a multi-system infectious disease with broad-spectrum manifestations,
including changes in host metabolic processes connected to the disease pathogenesis …

Desorption Separation Ionization Mass Spectrometry (DSI-MS) for Rapid Analysis of COVID-19

Y Wang, W Ma, Y Qu, K Jia, J Liu, Y Li, L Jiang… - Analytical …, 2024 - ACS Publications
During the coronavirus disease 2019 (COVID-19) pandemic, which has witnessed over 772
million confirmed cases and over 6 million deaths globally, the outbreak of COVID-19 has …

Common molecular signatures between coronavirus infection and Alzheimer's disease reveal targets for drug development

M Abyadeh, VK Yadav, A Kaya - Journal of Alzheimer's …, 2023 - content.iospress.com
Background: Cognitive decline is a common consequence of COVID-19, and studies
suggest a link between COVID-19 and Alzheimer's disease (AD). However, the molecular …

Integrated metabolic and inflammatory signatures associated with severity of, fatality of, and recovery from COVID-19

LG Gardinassi, CP Servian, GS Lima… - Microbiology …, 2023 - Am Soc Microbiol
Severe manifestations of coronavirus disease 2019 (COVID-19) and mortality have been
associated with physiological alterations that provide insights into the pathogenesis of the …

ML-based clinical decision support models based on metabolomics data

M Burdukiewicz, J Chilimoniuk, K Grzesiak… - TrAC Trends in …, 2024 - Elsevier
Abstract Machine learning-based clinical decision support models in healthcare emulate
clinicians' cognitive processes, leveraging artificial intelligence to analyze intricate medical …

Systematic Mendelian randomization study of the effect of gut microbiome and plasma metabolome on severe COVID-19

H Yan, S Zhao, HX Huang, P Xie, XH Cai… - Frontiers in …, 2023 - frontiersin.org
Background COVID-19 could develop severe respiratory symptoms in certain infected
patients, especially in the patients with immune disorders. Gut microbiome and plasma …

Nucleotide, Phospholipid, and Kynurenine Metabolites Are Robustly Associated with COVID-19 Severity and Time of Plasma Sample Collection in a Prospective …

HAS Chatelaine, Y Chen, J Braisted, SH Chu… - International Journal of …, 2023 - mdpi.com
Understanding the molecular underpinnings of disease severity and progression in human
studies is necessary to develop metabolism-related preventative strategies for severe …