[HTML][HTML] Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
The human innate and adaptive immune systems consist of effector cells producing
cytokines (interleukins, interferons, chemokines, and numerous other mediators). Usually, a …

[HTML][HTML] Cognitive impairment after COVID-19—a review on objective test data

R Daroische, MS Hemminghyth, TH Eilertsen… - Frontiers in …, 2021 - frontiersin.org
Objective: The aim was to conduct a review on the literature on objective cognitive
impairment in patients after COVID-19. Methods: We performed a literature review and …

[HTML][HTML] Laboratory biomarkers for diagnosis and prognosis in COVID-19

D Battaglini, M Lopes-Pacheco… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes a wide spectrum of
clinical manifestations, with progression to multiorgan failure in the most severe cases …

[HTML][HTML] Past, present and (foreseeable) future of biological anti-TNF alpha therapy

GM Leone, K Mangano, MC Petralia, F Nicoletti… - Journal of Clinical …, 2023 - mdpi.com
Due to the key role of tumor necrosis factor-alpha (TNF-α) in the pathogenesis of
immunoinflammatory diseases, TNF-α inhibitors have been successfully developed and …

[HTML][HTML] Mesenchymal stem cell treatment for COVID-19

R Xu, Z Feng, FS Wang - EBioMedicine, 2022 - thelancet.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused a
global pandemic since late 2019 that resulted in more than 360 million population infection …

COVID‐19 immunopathology: from acute diseases to chronic sequelae

M Arish, W Qian, H Narasimhan… - Journal of medical …, 2023 - Wiley Online Library
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …

[HTML][HTML] Safety and long-term improvement of mesenchymal stromal cell infusion in critically COVID-19 patients: a randomized clinical trial

CLK Rebelatto, AC Senegaglia, CL Franck… - Stem cell research & …, 2022 - Springer
Background COVID-19 is a multisystem disease that presents acute and persistent
symptoms, the postacute sequelae (PASC). Long-term symptoms may be due to …

[HTML][HTML] SARS-CoV-2 ORF3a sensitizes cells to ferroptosis via Keap1-NRF2 axis

L Liu, J Du, S Yang, B Zheng, J Shen, J Huang, L Cao… - Redox Biology, 2023 - Elsevier
Viral infection-induced cell death has long been considered as a double-edged sword in the
inhibition or exacerbation of viral infections. Patients with severe Coronavirus Disease 2019 …

[HTML][HTML] Safety and efficacy study of allogeneic human menstrual blood stromal cells secretome to treat severe COVID-19 patients: clinical trial phase I & II

M Fathi-Kazerooni, S Fattah-Ghazi, M Darzi… - Stem Cell Research & …, 2022 - Springer
Abstract Background Cell-free Mesenchymal stromal cells (MSCs) have been considered
due to their capacity to modulate the immune system and suppress cytokine storms caused …

[HTML][HTML] Neurotropism of SARS-CoV-2 and neurological diseases of the central nervous system in COVID-19 patients

S Veleri - Experimental brain research, 2022 - Springer
The devastating COVID-19 pandemic is caused by the SARS-CoV-2 virus. It primarily affects
the lung and induces acute respiratory distress leading to a decrease in oxygen supply to …