Highlights•Electrospinning systems (ES) have huge potential for the development of promising ocular drug delivery systems.•Ocular applications of currently researched ES …
A Martínez-Vacas, J Di Pierdomenico… - Redox biology, 2022 - Elsevier
The aim of our work was to study whether taurine administration has neuroprotective effects in dystrophic Royal College of Surgeons (RCS) rats, suffering retinal degeneration …
Y Yao, J Li, Y Zhou, S Wang, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Macrophages/microglia are immune system defense and homeostatic cells that develop from bone marrow progenitor cells. According to the different phenotypes and immune …
G Li, S Liu, W Chen, Z Jiang, Y Luo… - Advanced …, 2022 - Wiley Online Library
Replenishing the retina with retinal pigment epithelial (RPE) cells derived from pluripotent stem cells (PSCs) has great promise for treating retinal degenerative diseases, but it is …
M Norte-Muñoz, A Gallego-Ortega… - Stem cell research & …, 2022 - Springer
Background Advanced therapies using adult mesenchymal stromal cells (MSCs) for neurodegenerative diseases are not effectively translated into the clinic. The cross talk …
Purpose To study and compare effects of syngeneic bone marrow mononuclear stem cells (BM‐MNCs) transplants on inherited retinal degeneration in two animal models with different …
A Martínez-Vacas, J Di Pierdomenico… - International Journal of …, 2021 - mdpi.com
We investigate glial cell activation and oxidative stress induced by taurine deficiency secondary to β-alanine administration and light exposure. Two months old Sprague-Dawley …
T Igarashi, I Ohsawa, M Kobayashi, K Miyazaki… - Scientific Reports, 2022 - nature.com
Retinitis pigmentosa (RP) is a genetically heterogeneous group of inherited retinal disorders involving the progressive dysfunction of photoreceptors and the retinal pigment epithelium …
JS Peña, M Vazquez - Frontiers in bioscience (Landmark edition), 2022 - ncbi.nlm.nih.gov
Progressive and irreversible vision loss in mature and aging adults creates a health and economic burden, worldwide. Despite the advancements of many contemporary therapies to …