Taurine: A source and application for the relief of visual fatigue

H Duan, W Song, J Guo, W Yan - Nutrients, 2023 - mdpi.com
According to reports, supplementation with appropriate doses of taurine may help to reduce
visual fatigue. Presently, some progress has been made in research related to taurine in eye …

[HTML][HTML] Ocular application of electrospun materials for drug delivery and cellular therapies

D Mishra, S Gade, V Pathak, LK Vora, K Mcloughlin… - Drug Discovery …, 2023 - Elsevier
Highlights•Electrospinning systems (ES) have huge potential for the development of
promising ocular drug delivery systems.•Ocular applications of currently researched ES …

[HTML][HTML] Systemic taurine treatment affords functional and morphological neuroprotection of photoreceptors and restores retinal pigment epithelium function in RCS …

A Martínez-Vacas, J Di Pierdomenico… - Redox biology, 2022 - Elsevier
The aim of our work was to study whether taurine administration has neuroprotective effects
in dystrophic Royal College of Surgeons (RCS) rats, suffering retinal degeneration …

Macrophage/microglia polarization for the treatment of diabetic retinopathy

Y Yao, J Li, Y Zhou, S Wang, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Macrophages/microglia are immune system defense and homeostatic cells that develop
from bone marrow progenitor cells. According to the different phenotypes and immune …

Acellularized uvea hydrogel as novel injectable platform for cell‐based delivering treatment of retinal degeneration and optimizing retinal organoids inducible system

G Li, S Liu, W Chen, Z Jiang, Y Luo… - Advanced …, 2022 - Wiley Online Library
Replenishing the retina with retinal pigment epithelial (RPE) cells derived from pluripotent
stem cells (PSCs) has great promise for treating retinal degenerative diseases, but it is …

Immune recognition of syngeneic, allogeneic and xenogeneic stromal cell transplants in healthy retinas

M Norte-Muñoz, A Gallego-Ortega… - Stem cell research & …, 2022 - Springer
Background Advanced therapies using adult mesenchymal stromal cells (MSCs) for
neurodegenerative diseases are not effectively translated into the clinic. The cross talk …

Intravitreal and subretinal syngeneic bone marrow mononuclear stem cell transplantation improves photoreceptor survival but does not ameliorate retinal function in …

J Di Pierdomenico, A Gallego‐Ortega… - Acta …, 2022 - Wiley Online Library
Purpose To study and compare effects of syngeneic bone marrow mononuclear stem cells
(BM‐MNCs) transplants on inherited retinal degeneration in two animal models with different …

Glial cell activation and oxidative stress in retinal degeneration induced by β-alanine caused taurine depletion and light exposure

A Martínez-Vacas, J Di Pierdomenico… - International Journal of …, 2021 - mdpi.com
We investigate glial cell activation and oxidative stress induced by taurine deficiency
secondary to β-alanine administration and light exposure. Two months old Sprague-Dawley …

Drinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice

T Igarashi, I Ohsawa, M Kobayashi, K Miyazaki… - Scientific Reports, 2022 - nature.com
Retinitis pigmentosa (RP) is a genetically heterogeneous group of inherited retinal disorders
involving the progressive dysfunction of photoreceptors and the retinal pigment epithelium …

[HTML][HTML] Harnessing the neuroprotective behaviors of Müller glia for retinal repair

JS Peña, M Vazquez - Frontiers in bioscience (Landmark edition), 2022 - ncbi.nlm.nih.gov
Progressive and irreversible vision loss in mature and aging adults creates a health and
economic burden, worldwide. Despite the advancements of many contemporary therapies to …