Ebola viral disease (EVD) is a highly infectious and potentially fatal illness with a case
fatality rate ranging from 25% to 90%. To effectively control its spread, there is a need for …

Ebola virus (EBOV) causes a severe haemorrhagic fever in humans and has a mortality rate
over 50%. With no licensed drug treatments available, EBOV poses a significant threat …

The Filoviridae family of negative-sense, single-stranded RNA (ssRNA) viruses is comprised
of two species of Marburgvirus (MARV and RAVV) and five species of Ebolavirus, ie Zaire …

The Ebola virus (EBOV) transcriptional regulation involves host protein phosphatases PP1
and PP2A, which dephosphorylate the transcriptional cofactor of EBOV polymerase VP30 …

Polyamides have been shown to bind double-stranded DNA by complementing the
curvature of the minor groove and forming various hydrogen bonds with DNA. Several …

The family Filoviridae comprises many notorious viruses, such as Ebola virus (EBOV) and
Marburg virus (MARV), that can infect humans and nonhuman primates. Lloviu virus (LLOV) …

Ebolavirus is the pathogen for Ebola Hemorrhagic Fever (EHF). This disease exhibits a high
fatality rate and has recently reached a historically epidemic proportion in West Africa. Out of …

Ebola virus (EBOV) harbors an RNA genome encapsidated by nucleoprotein (NP) along
with other viral proteins to form a nucleocapsid complex. Previous Cryo-eletron tomography …

Virus from the Mononegavirales order share common features ranging from virion structure
arrangement to mechanisms of replication and transcription. One of them is the way the …

The Ebola virus, a member of the Filoviridae family, causes severe hemorrhagic fever in
humans. Filamentous virions contain a helical nucleocapsid responsible for genome …