Epigenetic Changes in Alzheimer's Disease: DNA Methylation and Histone Modification
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by
progressive cognitive decline and memory loss, imposing a significant burden on affected …
progressive cognitive decline and memory loss, imposing a significant burden on affected …
Clearing truncated tau protein restores neuronal function and prevents microglia activation in tauopathy mice
A Martin-Avila, SR Modak, HB Rajamohamedsait… - bioRxiv, 2024 - biorxiv.org
Tau protein truncated at aspartate 421 (Asp421) is a characteristic feature of Alzheimer's
disease (AD) and other tauopathies. It is likely to have a role in their pathogenesis by …
disease (AD) and other tauopathies. It is likely to have a role in their pathogenesis by …