A nonlinear mathematical model which includes synergistic effects of chemo-and
immunotherapy is analyzed (both analytically and numerically) as an optimal control …

Immunotherapy is one of the most recent approaches in cancer therapy. In this paper, a
mathematical model of tumor-immune interaction with periodically pulsed immunotherapy …

In this work, we propose a stochastic generalization of deterministic coupled TNDL model
with drug interventions, that provides an interplay between Tumor cells (T), Natural killer …

The advancements in next-generation sequencing have made it possible to effectively
detect somatic mutations, which has led to the development of personalized neoantigen …

The paper uses nine coupled ordinary differential equations (ODEs) to describe a tumor-
immune competitive system. The model is then reduced to four nonlinear coupled ODEs …

We modify the classical virus dynamics model by incorporating an immune response with
fixed or fluctuating vaccination frequencies and dosages to obtain a system of impulsive …

The release of tumor antigens during traditional cancer treatments leads to a stimulation of
the immune response which provides synergistic effects these treatments have when …

A mathematical model of the tumor–immune system interactions is presented. The model
includes the primary cell populations involved in CD4+ T cells mediated regression of the …

We develop a mathematical model that describes the tumour–immune interaction and the
effect on it of pulsed immunotherapy, based on the administration of adoptive cellular …

We investigate a mathematical model that delineates the nonlinear dynamics of tumor-
immune interplay by considering the roles of immunotherapy and chemotherapy. The …