Intranasal COVID-19 vaccines: From bench to bed

A Alu, L Chen, H Lei, Y Wei, X Tian, X Wei - EBioMedicine, 2022 - thelancet.com
Currently licensed COVID-19 vaccines are all designed for intramuscular (IM) immunization.
However, vaccination today failed to prevent the virus infection through the upper respiratory …

SARS‐CoV‐2 variants and vulnerability at the global level

VP Chavda, AB Patel… - Journal of medical …, 2022 - Wiley Online Library
Numerous variants of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
pandemic have evolved. Viral variants may evolve with harmful susceptibility to the immunity …

[HTML][HTML] Mucosal immune response in BNT162b2 COVID-19 vaccine recipients

L Azzi, D Dalla Gasperina, G Veronesi, M Shallak… - …, 2022 - thelancet.com
Background Although the BNT162b2 COVID-19 vaccine is known to induce IgG neutralizing
antibodies in serum protecting against COVID-19, it has not been studied in detail whether it …

[HTML][HTML] Artificial intelligence in pharmaceutical technology and drug delivery design

LK Vora, AD Gholap, K Jetha, RRS Thakur, HK Solanki… - Pharmaceutics, 2023 - mdpi.com
Artificial intelligence (AI) has emerged as a powerful tool that harnesses anthropomorphic
knowledge and provides expedited solutions to complex challenges. Remarkable …

Nanoparticle-based delivery systems for vaccines

R Bezbaruah, VP Chavda, L Nongrang, S Alom… - Vaccines, 2022 - mdpi.com
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …

SARS-CoV-2 Omicron variants: burden of disease, impact on vaccine effectiveness and need for variant-adapted vaccines

S Pather, SA Madhi, BJ Cowling, P Moss… - Frontiers in …, 2023 - frontiersin.org
The highly transmissible Omicron (B. 1.1. 529) variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) was first detected in late 2021. Initial Omicron waves were …

DNA vaccines for SARS-CoV-2: toward third-generation vaccination era

VP Chavda, R Pandya… - Expert review of …, 2021 - Taylor & Francis
ABSTRACT Introduction: Coronavirus outbreak 2019 (COVID-19) has affected all the
corners of the globe and created chaos to human life. In order to put some control on the …

A global picture: therapeutic perspectives for COVID-19

VP Chavda, C Kapadia, S Soni, R Prajapati… - …, 2022 - Future Medicine
The COVID-19 pandemic is a lethal virus outbreak by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), which has severely affected human lives and the global …

Recent advances in mucoadhesive interface materials, mucoadhesion characterization, and technologies

IS Bayer - Advanced Materials Interfaces, 2022 - Wiley Online Library
Mucoadhesion is an extremely important field of adhesion science and the comprehensive
understanding and modulation of mucoadhesion can lead to lifesaving materials and …

Fast-track development of vaccines for SARS-CoV-2: the shots that saved the world

VP Chavda, Q Yao, LK Vora, V Apostolopoulos… - Frontiers in …, 2022 - frontiersin.org
In December 2019, an outbreak emerged of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) which leads to coronavirus disease 2019 (COVID-19). The World Health …