Validation of biomarkers of aging

M Moqri, C Herzog, JR Poganik, K Ying, JN Justice… - Nature medicine, 2024 - nature.com
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …

Biomarkers of aging for the identification and evaluation of longevity interventions

M Moqri, C Herzog, JR Poganik, J Justice, DW Belsky… - Cell, 2023 - cell.com
With the rapid expansion of aging biology research, the identification and evaluation of
longevity interventions in humans have become key goals of this field. Biomarkers of aging …

Improving cognitive function with nutritional supplements in aging: a comprehensive narrative review of clinical studies investigating the effects of vitamins, minerals …

M Fekete, A Lehoczki, S Tarantini, V Fazekas-Pongor… - Nutrients, 2023 - mdpi.com
Cognitive impairment and dementia are burgeoning public health concerns, especially
given the increasing longevity of the global population. These conditions not only affect the …

[PDF][PDF] Geroscience and pathology: a new frontier in understanding age-related diseases

M Fekete, D Major, A Feher… - Pathology and …, 2024 - por-journal.com
Geroscience, an emerging discipline at the intersection of aging and disease, seeks to
understand the relationship between the aging process and pathogenesis of age-related …

Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop

TE Brinkley, JN Justice, S Basu, SR Bauer, KP Loh… - Geroscience, 2022 - Springer
Biologic aging reflects the genetic, molecular, and cellular changes underlying the
development of morbidity and mortality with advancing chronological age. As several …

Signs of aging in midlife: physical function and sex differences in microbiota

R Tzemah-Shahar, S Turjeman, E Sharon, G Gamliel… - Geroscience, 2024 - Springer
Microbiota composition has been linked to physical activity, health measures, and biological
age, but a shared profile has yet to be shown. The aim of this study was to examine the …

Probiotics-its functions and influence on the ageing process: A comprehensive review

P Choudhary, D Kathuria, S Suri, A Bahndral… - Food Bioscience, 2023 - Elsevier
The microbiota of the gastrointestinal tract is one of the most intricate ecosystems found in
nature. More than a thousand different bacterial species have been identified in the gut …

Lipid emulsion structure, digestion behavior, physiology, and health: a scoping review and future directions

E Dassoff, A Shireen, A Wright - Critical Reviews in Food Science …, 2023 - Taylor & Francis
Research investigating the effects of the food matrix on health is needed to untangle many
unresolved questions in nutritional science. Emulsion structure plays a fundamental role in …

Targeting the epigenetically older individuals for geroprotective trials: The use of DNA methylation clocks

E Sandalova, AB Maier - Biogerontology, 2024 - Springer
Chronological age is the most important risk factor for the incidence of age-related diseases.
The pace of ageing determines the magnitude of that risk and can be expressed as …

[PDF][PDF] Validation of biomarkers of aging

Biomarkers of Aging Consortium - Nature Medicine, 2024 - research.ed.ac.uk
Brain Development Network, Canadian Institute for Advanced Research and SocioMed
Research 87 Nucleus, Universidad Mayor, Santiago, Chile. DB is an inventor of …