[HTML][HTML] A review of disintegration mechanisms and measurement techniques
D Markl, JA Zeitler - Pharmaceutical research, 2017 - Springer
Pharmaceutical solid dosage forms (tablets or capsules) are the predominant form to
administer active pharmaceutical ingredients (APIs) to the patient. Tablets are typically …
administer active pharmaceutical ingredients (APIs) to the patient. Tablets are typically …
[HTML][HTML] Application of artificial neural networks in the process analytical technology of pharmaceutical manufacturing—a review
Industry 4.0 has started to transform the manufacturing industries by embracing
digitalization, automation, and big data, aiming for interconnected systems, autonomous …
digitalization, automation, and big data, aiming for interconnected systems, autonomous …
[HTML][HTML] Real-time release testing of dissolution based on surrogate models developed by machine learning algorithms using NIR spectra, compression force and …
In this work spectroscopic measurements, process data and Critical Material Attributes
(CMAs) are used to predict the in vitro dissolution profile of sustained-release tablets with …
(CMAs) are used to predict the in vitro dissolution profile of sustained-release tablets with …
A quality by design approach in oral extended release drug delivery systems: where we are and where we are going?
Background Oral extended release (ER) delivery systems have quickly gained increasing
importance because of their ability to maintain drug levels in the blood more consistently …
importance because of their ability to maintain drug levels in the blood more consistently …
[HTML][HTML] Predicting complexation performance between cyclodextrins and guest molecules by integrated machine learning and molecular modeling techniques
Q Zhao, Z Ye, Y Su, D Ouyang - Acta Pharmaceutica Sinica B, 2019 - Elsevier
Most pharmaceutical formulation developments are complex and ideal formulations are
generally obtained after extensive experimentation. Machine learning is increasingly …
generally obtained after extensive experimentation. Machine learning is increasingly …
[HTML][HTML] Predicting oral disintegrating tablet formulations by neural network techniques
Oral disintegrating tablets (ODTs) are a novel dosage form that can be dissolved on the
tongue within 3 min or less especially for geriatric and pediatric patients. Current ODT …
tongue within 3 min or less especially for geriatric and pediatric patients. Current ODT …
Applications of machine learning in solid oral dosage form development
H Lou, B Lian, MJ Hageman - Journal of Pharmaceutical Sciences, 2021 - Elsevier
This review comprehensively summarizes the application of machine learning in solid oral
dosage form development over the past three decades. In both academia and industry …
dosage form development over the past three decades. In both academia and industry …
[HTML][HTML] Performance appraisal of Trichoderma viride based novel tablet and powder formulations for management of Fusarium wilt disease in chickpea
PC Pradhan, A Mukhopadhyay, R Kumar… - Frontiers in Plant …, 2022 - frontiersin.org
In developing a Trichoderma viride-based biocontrol program for Fusarium wilt disease in
chickpea, the choice of the quality formulation is imperative. In the present study, two types …
chickpea, the choice of the quality formulation is imperative. In the present study, two types …
Application of artificial intelligence in pharmaceutical and biomedical studies
Background: Artificial intelligence (AI) is the way to model human intelligence to accomplish
certain tasks without much intervention of human beings. The term AI was first used in 1956 …
certain tasks without much intervention of human beings. The term AI was first used in 1956 …
[HTML][HTML] A prediction model based on artificial intelligence techniques for disintegration time and hardness of fast disintegrating tablets in pre-formulation tests
M Momeni, M Afkanpour, S Rakhshani… - BMC Medical Informatics …, 2024 - Springer
Background The pharmaceutical industry is continually striving to innovate drug
development and formulation processes. Orally disintegrating tablets (ODTs) have gained …
development and formulation processes. Orally disintegrating tablets (ODTs) have gained …