Changing epidemiology of hepatocellular carcinoma in Asia

C Zhang, Y Cheng, S Zhang, J Fan, Q Gao - Liver International, 2022 - Wiley Online Library
Liver cancer is the fifth most common cancer and the second leading cause of malignant
death in Asia, and Asia reports 72.5% of the world's cases in 2020. As the most common …

The clinical management of hepatocellular carcinoma worldwide: A concise review and comparison of current guidelines: 2022 update

N Wen, Y Cai, F Li, H Ye, W Tang, P Song… - Bioscience …, 2022 - jstage.jst.go.jp
Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the second
leading cause of cancer-related mortality worldwide. This review is an updated version that …

Nivolumab versus sorafenib in advanced hepatocellular carcinoma (CheckMate 459): a randomised, multicentre, open-label, phase 3 trial

T Yau, JW Park, RS Finn, AL Cheng, P Mathurin… - The Lancet …, 2022 - thelancet.com
Background Single-agent nivolumab showed durable responses, manageable safety, and
promising survival in patients with advanced hepatocellular carcinoma in the phase 1–2 …

[PDF][PDF] Arterial chemotherapy of oxaliplatin plus fluorouracil versus sorafenib in advanced hepatocellular carcinoma: a biomolecular exploratory, randomized, phase III …

N Lyu, X Wang, JB Li, JF Lai, QF Chen… - Journal of Clinical …, 2022 - drive.google.com
METHODS In this open-label, phase III trial, patients with advanced HCC, previously
untreated with systemic therapy, were randomly assigned in a 1: 1 ratio to receive HAIC-FO …

Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

[HTML][HTML] Atezolizumab plus bevacizumab followed by curative conversion (ABC conversion) in patients with unresectable, TACE-unsuitable intermediate-stage …

M Kudo - Liver cancer, 2022 - karger.com
Atezolizumab plus bevacizumab (Atezo/Bev) followed by curative conversion (ABC
conversion) therapy is very effective in the treatment of unresectable, transarterial …

Imaging to predict prognosis in hepatocellular carcinoma: current and future perspectives

M Ronot, V Chernyak, A Burgoyne, J Chang, H Jiang… - Radiology, 2023 - pubs.rsna.org
The focus of hepatocellular carcinoma (HCC) research for many years has been on
noninvasive diagnosis. Standardized systematic algorithms composed of combinations of …

Final results of TACTICS: a randomized, prospective trial comparing transarterial chemoembolization plus sorafenib to transarterial chemoembolization alone in …

M Kudo, K Ueshima, M Ikeda, T Torimura, N Tanabe… - Liver cancer, 2022 - karger.com
Introduction: Several clinical trials comparing the efficacy and safety of transarterial
chemoembolization (TACE) plus molecular-targeted agents versus TACE alone revealed no …

Nonalcoholic fatty liver disease and hepatocellular carcinoma: Insights in epidemiology, pathogenesis, imaging, prevention and therapy

SA Polyzos, L Chrysavgis, ID Vachliotis… - Seminars in Cancer …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is estimated to be the third leading cause of cancer-related
mortality and is characterized by low survival rates. Nonalcoholic fatty liver disease (NAFLD) …

Personalised management of patients with hepatocellular carcinoma: a multiparametric therapeutic hierarchy concept

A Vitale, G Cabibbo, M Iavarone, L Viganò… - The Lancet …, 2023 - thelancet.com
Advances in the surgical and systemic therapeutic landscape of hepatocellular carcinoma
have increased the complexity of patient management. A dynamic adaptation of the …