Chromatin is the physical substrate of the genome that carries the DNA sequence and
ensures its proper functions and regulation in the cell nucleus. While a lot is known about …

The lifespan is influenced by adverse childhood experiences that create predispositions to
poor health outcomes. Here we propose an allostatic framework of childhood experiences …

Background Childhood maltreatment is associated with depression and cardiometabolic
disease in adulthood. However, the relationships with these two diseases have so far only …

Background Social determinants of health (SDoHs) are nonmedical factors that significantly
impact health and longevity. We found no published reviews on the biology of SDoHs in …

Children that survive leukemia are at an increased risk for cognitive difficulties. A better
understanding of the neurobiological changes in response to early life chemotherapy will …

Childhood maltreatment is a risk factor for psychopathologies, and influences brain
development at specific periods, particularly during early childhood and adolescence. This …

Background This is the first study to investigate the longitudinal association between
prenatal and perinatal psychiatric hospitalizations and academic achievements in …

Abstract Study Objectives Exposure to postnatal chronic intermittent hypoxia (pCIH), as
experienced in sleep-disordered breathing, is a risk factor for developing cardiorespiratory …

Nearly one percent of children in the US experience childhood neglect or abuse, which can
incite lifelong emotional and behavioral disorders. Many studies investigating the neural …

In this review, we focus on prenatal opioid exposure (POE) given the significant concern for
the mental health outcomes of children with parents affected by opioid use disorder (OUD) in …