Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications—risks and mitigation
M Kropp, O Golubnitschaja, A Mazurakova… - Epma Journal, 2023 - Springer
Proliferative diabetic retinopathy (PDR) the sequel of diabetic retinopathy (DR), a frequent
complication of diabetes mellitus (DM), is the leading cause of blindness in the working-age …
complication of diabetes mellitus (DM), is the leading cause of blindness in the working-age …
Smart contact lenses as wearable ophthalmic devices for disease monitoring and health management
The eye contains a complex network of physiological information and biomarkers for
monitoring disease and managing health, and ocular devices can be used to effectively …
monitoring disease and managing health, and ocular devices can be used to effectively …
[HTML][HTML] A review of biological targets and therapeutic approaches in the management of triple-negative breast cancer
Background Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …
Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care
A Mazurakova, L Koklesova, M Samec, E Kudela… - EPMA Journal, 2022 - Springer
Breast cancer incidence is actually the highest one among all cancers. Overall breast cancer
management is associated with challenges considering risk assessment and predictive …
management is associated with challenges considering risk assessment and predictive …
Applications of tandem mass spectrometry (MS/MS) in protein analysis for biomedical research
AN Neagu, M Jayathirtha, E Baxter, M Donnelly… - Molecules, 2022 - mdpi.com
Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of
methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted …
methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted …
Characterization of oral and gut microbiome and plasma metabolomics in COVID-19 patients after 1-year follow-up
GY Cui, BC Rao, ZH Zeng, XM Wang, T Ren… - Military Medical …, 2022 - Springer
Background Due to the outbreak and rapid spread of coronavirus disease 2019 (COVID-19),
more than 160 million patients have become convalescents worldwide to date. Significant …
more than 160 million patients have become convalescents worldwide to date. Significant …
[HTML][HTML] Significance of flavonoids targeting PI3K/Akt/HIF-1α signaling pathway in therapy-resistant cancer cells–a potential contribution to the predictive, preventive …
A Mazurakova, L Koklesova, SH Csizmár… - Journal of Advanced …, 2024 - Elsevier
Background Cancer management faces multiple obstacles, including resistance to current
therapeutic approaches. In the face of challenging microenvironments, cancer cells adapt …
therapeutic approaches. In the face of challenging microenvironments, cancer cells adapt …
Prostate cancer treatment costs increase more rapidly than for any other cancer—how to reverse the trend?
Abstract According to GLOBOCAN, about 1.41 million new prostate cancer (PCa) cases
were registered in the year 2020 globally. The corresponding socio-economic burden is …
were registered in the year 2020 globally. The corresponding socio-economic burden is …
Clarifying the effect of gut microbiota on allergic conjunctivitis risk is instrumental for predictive, preventive, and personalized medicine: a Mendelian randomization …
K Liu, Y Cai, K Song, R Yuan, J Zou - EPMA Journal, 2023 - Springer
Background Allergic conjunctivitis is an ocular immune disease which affects the
conjunctiva, eyelids, and cornea. Growing evidence implicates the gut microbiota in …
conjunctiva, eyelids, and cornea. Growing evidence implicates the gut microbiota in …
unique metabolic signature of proliferative retinopathy in the tear fluid of diabetic patients with comorbidities—preliminary data for PPPM validation
M Kropp, E De Clerck, TTKS Vo, G Thumann… - EPMA Journal, 2023 - Springer
Abstract Type 2 diabetes (T2DM) defined as the adult-onset type that is primarily not insulin-
dependent, comprises over 95% of all diabetes mellitus (DM) cases. According to global …
dependent, comprises over 95% of all diabetes mellitus (DM) cases. According to global …