Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

[HTML][HTML] Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

D Matuozzo, E Talouarn, A Marchal, P Zhang, J Manry… - Genome medicine, 2023 - Springer
Background We previously reported that impaired type I IFN activity, due to inborn errors of
TLR3-and TLR7-dependent type I interferon (IFN) immunity or to autoantibodies against type …

[HTML][HTML] TMPRSS2 polymorphism (rs12329760) and the severity of the COVID-19 in Iranian population

A Yaghoobi, JS Lord, JS Rezaiezadeh… - PLoS …, 2023 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been responsible for
the recent pandemic since early 2020. Due to the wide range of clinical symptoms of this …

[HTML][HTML] Diagnosis and stratification of COVID-19 infections using differential plasma levels of D-dimer: a two-center study from Saudi Arabia

A Alsrhani, A Alshomar, AY Elderdery, Z Rasheed… - Microbiology …, 2023 - mdpi.com
Background: D-dimer, generated upon the degradation of fibrin, is extensively used to detect
thrombosis in various diseases. It is also explored as a marker for thrombosis in cases with …

[HTML][HTML] Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19

A Valenzuela-Fernández… - … in bioengineering and …, 2022 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the
associated coronavirus disease 2019 (COVID-19), which severely affect the respiratory …

Genetics of COVID‐19 and myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review

M Tziastoudi, C Cholevas, I Stefanidis… - Annals of Clinical …, 2022 - Wiley Online Library
Abstract COVID‐19 and ME/CFS present with some similar symptoms, especially physical
and mental fatigue. In order to understand the basis of these similarities and the possibility of …

[HTML][HTML] Better safe than sorry—Whole-genome sequencing indicates that missense variants are significant in susceptibility to COVID-19

D Słomian, J Szyda, P Dobosz, J Stojak… - PLoS …, 2023 - journals.plos.org
Undoubtedly, genetic factors play an important role in susceptibility and resistance to COVID-
19. In this study, we conducted the GWAS analysis. Out of 15,489,173 SNPs, we identified …

[PDF][PDF] Pathogen exposure misclassification can bias association signals in GWAS of infectious diseases when using population-based common control subjects

D Duchen, C Vergara, CL Thio, P Kundu… - The American Journal of …, 2023 - cell.com
Genome-wide association studies (GWASs) have been performed to identify host genetic
factors for a range of phenotypes, including for infectious diseases. The use of population …

Genome-Wide Association study of susceptibility to respiratory syncytial virus hospitalization in young children< 5 years of age

AM Egeskov-Cavling, M van Wijhe… - The Journal of …, 2023 - academic.oup.com
Background Worldwide, respiratory syncytial virus (RSV) infections are among the most
common causes of infant hospitalization. Host genetic factors influencing the risk and …

[HTML][HTML] First report on genome wide association study in western Indian population reveals host genetic factors for COVID-19 severity and outcome

R Pandit, I Singh, A Ansari, J Raval, Z Patel, R Dixit… - Genomics, 2022 - Elsevier
Different human races across the globe responded in a different way to the SARS-CoV-2
infection leading to different disease severity. Therefore, it is anticipated that host genetic …