A decade of FDA-approved drugs (2010–2019): trends and future directions

DG Brown, HJ Wobst - Journal of medicinal chemistry, 2021 - ACS Publications
A total of 378 novel drugs and 27 biosimilars approved by the US Food and Drug
Administration (FDA) between 2010 and 2019 were evaluated according to approval …

[HTML][HTML] Self-medication practices to prevent or manage COVID-19: A systematic review

A Quincho-Lopez, CA Benites-Ibarra… - PloS one, 2021 - journals.plos.org
Background Previous studies have assessed the prevalence and characteristics of self-
medication in COVID-19. However, no systematic review has summarized their findings …

[HTML][HTML] First and second waves of coronavirus disease-19: A comparative study in hospitalized patients in Reus, Spain

S Iftimie, AF López-Azcona, I Vallverdú… - PloS one, 2021 - journals.plos.org
Many countries have seen a two-wave pattern in reported cases of coronavirus disease-19
during the 2020 pandemic, with a first wave during spring followed by the current second …

SARS-CoV-2 mediated neuroinflammation and the impact of COVID-19 in neurological disorders

N Amruta, WH Chastain, M Paz, RJ Solch… - Cytokine & growth factor …, 2021 - Elsevier
SARS-CoV-2 is a novel coronavirus that severely affects the respiratory system, is the cause
of the COVID-19 pandemic, and is projected to result in the deaths of 2 million people …

Potential relationships between COVID-19 and the thyroid gland: an update

R Naguib - Journal of International Medical Research, 2022 - journals.sagepub.com
In this review, I aim to provide a complete overview of recent advances in knowledge
regarding severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)-induced thyroid …

[HTML][HTML] On the analysis of mortality risk factors for hospitalized COVID-19 patients: A data-driven study using the major Brazilian database

FSH de Souza, NS Hojo-Souza, BDO Batista… - PloS one, 2021 - journals.plos.org
Background Brazil became the epicenter of the COVID-19 epidemic in a brief period of a few
months after the first officially registered case. The knowledge of the epidemiological/clinical …

[HTML][HTML] Neutrophil extracellular traps (NETs) in severe SARS-CoV-2 lung disease

M Szturmowicz, U Demkow - International journal of molecular sciences, 2021 - mdpi.com
Neutrophil extracellular traps (NETs), built from mitochondrial or nuclear DNA, proteinases,
and histones, entrap and eliminate pathogens in the course of bacterial or viral infections …

[HTML][HTML] Amentoflavone derivatives significantly act towards the main protease (3CLPRO/MPRO) of SARS-CoV-2: in silico admet profiling, molecular docking …

D Dey, R Hossain, P Biswas, P Paul, MA Islam… - Molecular …, 2023 - Springer
SARS-CoV-2 is the foremost culprit of the novel coronavirus disease 2019 (nCoV-19 and/or
simply COVID-19) and poses a threat to the continued life of humans on the planet and …

A review on possible mechanistic insights of Nitazoxanide for repurposing in COVID-19

AS Lokhande, PV Devarajan - European Journal of Pharmacology, 2021 - Elsevier
The global pandemic of Coronavirus Disease 2019 (COVID-19) has brought the world to a
grinding halt. A major cause of concern is the respiratory distress associated mortality …

Thyroid disorders and SARS-CoV-2 infection: From pathophysiological mechanism to patient management

P Caron - Annales D'endocrinologie, 2020 - Elsevier
Abstract The World Health Organization (WHO) declared the COVID-19 epidemic to be a
global pandemic in March 2020. COVID-19 is an infection caused by SARS-CoV-2, a …