Thyroid-stimulating hormone alpha and beta subunit genes are negatively regulated by
thyroid hormone at the transcriptional level. Transient gene expression studies were used to …

The timing of oligodendrocyte development is regulated by thyroid hormone (TH) in vitro and
in vivo, but it is still uncertain which TH receptors mediate this regulation. TH acts through …

Genetic analysis in our laboratory of families with generalized thyroid hormone resistance
(GTHR) has demonstrated tight linkage with a locus, c-erbA beta, encoding a nuclear T3 …

The mechanism of action of thyroid hormones on bone is poorly understood. Thyroid
hormones may act on bone cells either indirectly by increasing secretion of growth hormone …

Longitudinal growth of the skeleton is a result of endochondral ossification that occurs at the
growth plate. Through a sequential process of cell proliferation, extracellular matrix …

Sertoli cell proliferation in the rat is completed by Days 15–20 postnatally. Thyroid hormones
appear to regulate the duration of Sertoli cell proliferation, affecting adult Sertoli cell number …

Introduction T HE pituitary glycoprotein hormone TSH is synthesized and secreted by the
thyrotropes in the anterior pituitary. TSH acts on the thyroid gland to increase the production …

The influence of thyroid hormone on estrogen actions has been demonstrated both in vivo
and in vitro. In transient transfection assays, the effects of liganded thyroid hormone …

ABSTRACT A characteristic feature of the obligatory control of amphibian metamorphosis by
thyroid hormones is the early acquisition of response of tadpole tissues to these hormones …

The intracellular thyroid hormone (TH) availability is influenced by different metabolic
pathways. Some of the changes in intracellular TH availability can be linked to changes in …