Background: Although diuretics are one of the most widely used drugs by nephrologists,
their antiproteinuric properties are not generally taken into consideration. Summary …

The prevalence of end-stage kidney disease (ESKD) continuously increases worldwide. The
increasing prevalence parallels the growth in the number of people with diabetes, which is …

The 3 baseline kidney function classification schemes were as follows:(1) estimated
glomerular filtration rate (eGFR) categories: chronic kidney disease (CKD) stage 1 (eGFR≥ …

Abstract Background The Y-AIDA study was designed to investigate the renal-and home
blood pressure (BP)-modulating effects of add-on dapagliflozin treatment in Japanese …

Hypoxia plays a role in the pathogenesis of acute kidney injury under diverse clinical
settings, including nephrotoxicity. Although some nephrotoxins exert direct renal …

Aim To assess whether the previously developed multivariable risk prediction framework
(PRE score) could predict the renal effects observed in the EXSCEL cardiovascular …

Aims: The EMPA-REG OUTCOME trial demonstrated that the sodium-glucose cotransporter-
2 inhibitor (SGLT2) empagliflozin reduces the risk of cardiovascular (CV) and kidney …

Aims: The LEADER trial demonstrated that the glucagon-like peptide-1 receptor agonist
(GLP1-RA) liraglutide reduces kidney and cardiovascular (CV) risk in patients with type 2 …

Type 2 diabetes mellitus is a major health problem worldwide with a steadily increasing
prevalence reaching epidemic proportions. The major concern is the increased morbidity …

Background: Risk factor-based equations are used to predict risk of kidney disease
progression in patients with type 2 diabetes order to guide treatment decisions. It is …