Nobiletin from citrus peel: a promising therapeutic agent for liver disease-pharmacological characteristics, mechanisms, and potential applications

Y Cheng, S Feng, C Sheng, C Yang, Y Li - Frontiers in Pharmacology, 2024 - frontiersin.org
Nobiletin (NOB) is a flavonoid derived from citrus peel that has potential as an alternative
treatment for liver disease. Liver disease is a primary health concern globally, and there is …

Involvement of Bile Acid Metabolism and Gut Microbiota in the Amelioration of Experimental Metabolism-Associated Fatty Liver Disease by Nobiletin

H Xu, M Yuan, K Niu, W Yang, M Jiang, L Zhang… - Molecules, 2024 - mdpi.com
Metabolism-associated fatty liver disease (MAFLD), a growing health problem worldwide, is
one of the major risks for the development of cirrhosis and liver cancer. Oral administration …

Sangyod rice extract mitigates insulin resistance in HepG2 cells and hepatic steatosis in diabetic rats via AMPK/mTOR/MAPK signaling pathways

W Hanchang, W Woonnoi, J Saetan, W Suttithumsatid… - Food Bioscience, 2024 - Elsevier
Non-alcoholic fatty liver disease (NAFLD), marked by inflammation, oxidative stress, and
insulin resistance (IR), often has a significant impact on public health. To date, Sangyod rice …

A review of the therapeutic effects of polyphenols on non-alcoholic fatty liver disease: Focus on oxidative stress

AA Soleimani, BO Sarajar, M Aliabadi… - Acta Biochimica …, 2024 - abi.tums.ac.ir
A large amount of research suggests that polyphenols may have health benefits, particularly
in metabolic disorders associated with obesity, such as non-alcoholic fatty liver (NAFLD) …