Guidelines for accurate application of green and white analytical concepts: Merits vs demerits with insights of significant milestones of assessment tools applied for …

SS Saleh, RH Obaydo, MA El Hamd, Y Rostom… - Microchemical …, 2024 - Elsevier
In recent years, there has been a growing focus in analytical research on the ecological and
sustainable aspects of analytical methodologies. However, it is necessary to apply the …

[HTML][HTML] Tailoring two white chromatographic platforms for simultaneous estimation of ritonavir-boosted nirmatrelvir in their novel pills: degradation, validation, and …

HS Elbordiny, NZ Alzoman, HM Maher, SI Aboras - RSC advances, 2023 - pubs.rsc.org
As the COVID-19 pandemic is not yet over, Pfizer has launched the novel pill
Paxlovid®(Nirmatrelvir (NMV) co-packaged with ritonavir (RIT)) as an effective medication …

[HTML][HTML] A microcrystalline cellulose/metal-organic framework hybrid for enhanced ritonavir dispersive solid phase microextraction from human plasma

FR Mansour, RM Abdelhameed, SF Hammad… - Carbohydrate Polymer …, 2024 - Elsevier
A hybrid of microcrystalline cellulose (MCC) with metal organic frame (MOF) was developed
as an efficient adsorbent for dispersive solid phase microextraction (dSPME) of ritonavir from …

Greenness, whiteness, and blueness assessment with spider chart solvents evaluation of HPTLC-densitometric method for quantifying a triple combination anti …

SA Mahmoud, AEF Abbas - Sustainable Chemistry and Pharmacy, 2024 - Elsevier
Tackling environmental, economic, and practical issues necessitate analytical methods
aligned with green and white chemistry principles. This study quantified a challenging …

[HTML][HTML] Homogeneous liquid–liquid microextraction coupled with HPLC/DAD for determination of nirmatrelvir and ritonavir as COVID-19 combination therapy in …

IA Abdallah, SF Hammad, A Bedair, FR Mansour - BMC chemistry, 2023 - Springer
The study reports the development of a high-performance liquid chromatography/diode
array detection method to measure the levels of nirmatrelvir and ritonavir in human plasma …

[PDF][PDF] Pharmacokinetic analysis of placental transfer of ritonavir as a component of paxlovid using microdialysis in pregnant rats

CK Sun, WH Lee, MH Yang, TH Tsai - Heliyon, 2024 - cell.com
Background Ritonavir is one of the most potent CYP3A4 inhibitor currently on the market,
and is often used together with other antiviral drugs to increase their bioavailability and …

Development and validation of a new RP-UPLC method for the simultaneous estimation of nirmatrelvir and ritonavir in bulk and copacked tablet dosage forms

S Pallavi, G Sowjanya - Research Journal of Pharmacy and …, 2023 - indianjournals.com
The objective of this work is to develop a simple, accurate, precise and validated RP-UPLC
method for effective simultaneous determination of nirmatrelvir and ritonavir in bulk and …

Spectrophotometric Determination of Amoxicillin Using New Organic Reagent via Different Analytical Methods

HAA Mahmood, R Sabah, NK Abood - Indonesian Journal of Chemistry - journal.ugm.ac.id
New and simple spectrophotometric method was applied for amoxicillin determination by
oxidative coupling with an organic reagent 1-(4-aminophenyl)-3-(5-(4-nitrophenyl)-furan-2 …