Current Status of Malaria Control and Elimination in Africa: Epidemiology, Diagnosis, Treatment, Progress and Challenges
J Li, HJ Docile, D Fisher, K Pronyuk, L Zhao - Journal of Epidemiology and …, 2024 - Springer
The African continent carries the greatest malaria burden in the world. Falciparum malaria
especially has long been the leading cause of death in Africa. Climate, economic factors …
especially has long been the leading cause of death in Africa. Climate, economic factors …
Assessing the Implementation Determinants of Pilot Malaria Vaccination Programs in Ghana, Kenya, and Malawi through a Complexity Lens: A Rapid Review Using a …
In 2019, national immunization programs in Ghana, Kenya, and Malawi commenced the
implementation of RTS, S/AS01 vaccination in large-scale pilot schemes. Understanding the …
implementation of RTS, S/AS01 vaccination in large-scale pilot schemes. Understanding the …
Policy uptake and implementation of the RTS, S/AS01 malaria vaccine in sub-Saharan African countries: status 2 years following the WHO recommendation
CB Osoro, E Ochodo, TK Kwambai, JA Otieno… - BMJ Global …, 2024 - gh.bmj.com
In October 2021, the WHO recommended the world's first malaria vaccine—RTS, S/AS01—
to prevent malaria in children living in areas with moderate-to-high transmission in sub …
to prevent malaria in children living in areas with moderate-to-high transmission in sub …
[HTML][HTML] A phase IIa, randomized, double-blind, safety, immunogenicity and efficacy trial of Plasmodium falciparum vaccine antigens merozoite surface protein 1 and …
JF Cummings, ME Polhemus, KE Kester… - Vaccine, 2024 - Elsevier
Background To improve the efficacy of Plasmodium falciparum malaria vaccine RTS,
S/AS02, we conducted a study in 2001 in healthy, malaria-naïve adults administered RTS …
S/AS02, we conducted a study in 2001 in healthy, malaria-naïve adults administered RTS …
Previous Malaria Exposures and Immune Dysregulation: Developing Strategies To Improve Malaria Vaccine Efficacy in Young Children.
KR Dobbs, HE Atieli, C Valim… - The American Journal of …, 2024 - europepmc.org
After several decades in development, two malaria vaccines based on the same antigen and
with very similar constructs and adjuvants, RTS, S/AS01 (RTS, S) and R21/Matrix-M (R21) …
with very similar constructs and adjuvants, RTS, S/AS01 (RTS, S) and R21/Matrix-M (R21) …
Genetic variation of the Plasmodium falciparum circumsporozoite protein in parasite isolates from Homabay County in Kenya
The Plasmodium falciparum Circumsporozoite Protein (PfCSP) has been used in
developing the RTS, S, and R21 malaria vaccines. However, genetic polymorphisms within …
developing the RTS, S, and R21 malaria vaccines. However, genetic polymorphisms within …
Safety and efficacy of R21/Matrix-M vaccine against and eradicate malaria infection
PV Rahaded, F Herawati - Science Midwifery, 2024 - midwifery.iocspublisher.org
Malaria continues to be a substantial health concern, characterised by elevated rates of
illness and death. The development of resistance to existing treatments poses unique …
illness and death. The development of resistance to existing treatments poses unique …
[HTML][HTML] Malaria Vaccines: Another Step Closer to Beating Malaria
JYI Join, S Us, JYI Blog, JYIS Tool - jyi.org
Over the next two years, nearly 18 million more live-saving doses of RTS, S/AS01–the first-
ever malaria vaccine–will be distributed throughout Africa. While the issues that have …
ever malaria vaccine–will be distributed throughout Africa. While the issues that have …
[HTML][HTML] Malaria vaccination in Africa: A mini-review of challenges and opportunities
Malaria remains an endemic public health concern in Africa, significantly contributing to
morbidity and mortality rates. The inadequacies of traditional prevention measures, like …
morbidity and mortality rates. The inadequacies of traditional prevention measures, like …