[HTML][HTML] From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?

JE Michalski, JS Kurche, DA Schwartz - Translational Research, 2022 - Elsevier
While the coronavirus disease 19 (COVID-19) pandemic has transformed the medical and
scientific communites since it was first reported in late 2019, we are only beginning to …

Parenchymal lung abnormalities following hospitalisation for COVID-19 and viral pneumonitis: a systematic review and meta-analysis

L Fabbri, S Moss, FA Khan, W Chi, J Xia, K Robinson… - Thorax, 2023 - thorax.bmj.com
Introduction Persisting respiratory symptoms in COVID-19 survivors may be related to
development of pulmonary fibrosis. We assessed the proportion of chest CT scans and …

Outcome of hospitalization for COVID-19 in patients with interstitial lung disease. An international multicenter study

TM Drake, AB Docherty, EM Harrison… - American journal of …, 2020 - atsjournals.org
Rationale: The impact of coronavirus disease (COVID-19) on patients with interstitial lung
disease (ILD) has not been established. Objectives: To assess outcomes in patients with ILD …

Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity

J Fadista, LM Kraven, J Karjalainen, SJ Andrews… - …, 2021 - thelancet.com
Background Idiopathic pulmonary fibrosis (IPF) is a complex lung disease, characterized by
progressive lung scarring. Severe COVID-19 is associated with substantial pneumonitis and …

The interaction between pulmonary fibrosis and COVID-19 and the application of related anti-fibrotic drugs

H Shen, N Zhang, Y Liu, X Yang, Y He, Q Li… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is a highly contagious respiratory disease, which mainly affects the lungs.
Critically ill patients are easily complicated by cytokine storms, acute respiratory distress …

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

LT Bui, NI Winters, MI Chung, C Joseph… - Nature …, 2021 - nature.com
Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus
disease-19 (COVID-19) and poor outcomes. Here, we analyze the transcriptomes of …

Post-viral parenchymal lung disease following COVID-19 and viral pneumonitis hospitalisation: A systematic review and meta-analysis

L Fabbri, S Moss, F Khan, W Chi, J Xia, KA Robinson… - Medrxiv, 2021 - medrxiv.org
Background Approximately half of COVID-19 survivors present persisting breathlessness,
which may include development of pulmonary fibrosis. Research Question What is the …

The multi-faceted extracellular matrix: Unlocking its secrets for understanding the perpetuation of lung fibrosis

M Nizamoglu, JK Burgess - Current Tissue Microenvironment Reports, 2021 - Springer
Abstract Purpose of Review Lung fibrosis is currently thought to stem from an aberrant
wound healing response after recurring (micro) injuries in the lung epithelium, together with …

Age-Related Dynamics of Lung-Resident Memory CD8+ T Cells in the Age of COVID-19

NP Goplen, IS Cheon, J Sun - Frontiers in immunology, 2021 - frontiersin.org
Following respiratory viral infections or local immunizations, lung resident-memory T cells
(TRM) of the CD8 lineage provide protection against the same pathogen or related …

Impact of the COVID-19 pandemic on the management of chronic noninfectious respiratory diseases

A Tiotiu, H Chong Neto, A Bikov, K Kowal… - Expert review of …, 2021 - Taylor & Francis
Introduction: The COVID-19 pandemic has challenged health care across the world, not just
by the severity of the disease and the high mortality rate but also by the consequences on …