[HTML][HTML] Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses

DM Morens, JK Taubenberger, AS Fauci - Cell host & microbe, 2023 - cell.com
Viruses that replicate in the human respiratory mucosa without infecting systemically,
including influenza A, SARS-CoV-2, endemic coronaviruses, RSV, and many other" …

[HTML][HTML] Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases

S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …

[HTML][HTML] Mucosal immunity: The missing link in comprehending SARS-CoV-2 infection and transmission

MW Russell, J Mestecky - Frontiers in immunology, 2022 - frontiersin.org
SARS-CoV-2 is primarily an airborne infection of the upper respiratory tract, which on
reaching the lungs causes the severe acute respiratory disease, COVID-19. Its first contact …

Infectious virus shedding duration reflects secretory IgA antibody response latency after SARS-CoV-2 infection

S Miyamoto, T Nishiyama, A Ueno… - Proceedings of the …, 2023 - National Acad Sciences
Infectious virus shedding from individuals infected with severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2) is used to estimate human-to-human transmission risk. Control …

Intranasal mRNA-LNP vaccination protects hamsters from SARS-CoV-2 infection

G Baldeon Vaca, M Meyer, A Cadete, CJ Hsiao… - Science …, 2023 - science.org
Intranasal vaccination represents a promising approach for preventing disease caused by
respiratory pathogens by eliciting a mucosal immune response in the respiratory tract that …

[HTML][HTML] SARS-CoV-2: phenotype, genotype, and characterization of different variants

M Saberiyan, E Karimi, Z Khademi, P Movahhed… - Cellular & molecular …, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus
disease 2019 (COVID-19), a major international public health concern. Because of very …

[HTML][HTML] The end or a New Era of development of SARS-CoV-2 virus: Genetic variants responsible for severe COVID-19 and clinical efficacy of the most commonly …

D Miteva, M Kitanova, H Batselova, S Lazova… - Vaccines, 2023 - mdpi.com
Although the chief of the World Health Organization (WHO) has declared the end of the
coronavirus disease 2019 (COVID-19) as a global health emergency, the disease is still a …

[HTML][HTML] Infection-or AZD1222 vaccine-mediated immunity reduces SARS-CoV-2 transmission but increases Omicron competitiveness in hamsters

JR Port, CK Yinda, JC Riopelle, ZA Weishampel… - Nature …, 2023 - nature.com
Limited data is available on the effect of vaccination and previous virus exposure on the
nature of SARS-CoV-2 transmission and immune-pressure on variants. To understand the …

Immunogenicity and protectivity of intranasally delivered vector-based heterologous prime-boost COVID-19 vaccine Sputnik V in mice and non-human primates

AI Tukhvatulin, IV Gordeychuk… - Emerging Microbes & …, 2022 - Taylor & Francis
Although unprecedented efforts aiming to stop the COVID-19 pandemic have been made
over the past two years, SARSCoV-2 virus still continues to cause intolerable health and …

[HTML][HTML] The BNT162b2 vaccine induces humoral and cellular immune memory to SARS-CoV-2 Wuhan strain and the Omicron variant in children 5 to 11 years of age

BL Cinicola, E Piano Mortari, AM Zicari… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 mRNA vaccines prevent severe COVID-19 by generating immune memory,
comprising specific antibodies and memory B and T cells. Although children are at low risk …