Executive summary The past six decades have seen remarkable improvements in health
outcomes for people with cystic fibrosis, which was once a fatal disease of infants and young …

The survival of patients with cystic fibrosis (CF) continues to improve. The discovery and
cloning of the CFTR gene more than 21 years ago led to the identification of the structure …

In patients with cystic fibrosis (CF), early intervention and prevention of lung disease is of
paramount importance. Principles to achieve this aim include early diagnosis of CF, regular …

There is wide agreement on the benefits of NBS for CF in terms of lowered disease severity,
decreased burden of care, and reduced costs. Risks are mainly associated with disclosure …

In November 2003, CDC and the Cystic Fibrosis Foundation cosponsored a workshop to
review the benefits and risks associated with newborn screening for cystic fibrosis (CF). This …

Objectives. Newborn screening for cystic fibrosis (CF) provides a model to investigate the
implications of applying multiple-mutation DNA testing in screening for any disorder in a …

Based on serial lung function measurements performed in 142 children (68 males; 74
females) with cystic fibrosis (CF), prospectively evaluated over an age range of 6 to 20 …

Newborn screening for cystic fibrosis offers the opportunity for early intervention and
improved outcomes. This summary, resulting from a workshop sponsored by the Cystic …

Objective: The aim of the study was to evaluate and compare faecal markers of intestinal
inflammation in children with cystic fibrosis (CF), and determine whether intestinal …

Although early diagnosis of cystic fibrosis (CF) can lead to nutritional benefits, there has
been uncertainty about pulmonary outcomes. Using a randomized controlled trial with …