Multifunctional and stimuli-responsive nanocarriers for targeted therapeutic delivery

J Majumder, T Minko - Expert opinion on drug delivery, 2021 - Taylor & Francis
Introduction Nanocarrier-based delivery systems offer multiple benefits to overcome
limitations of the traditional drug dosage forms, such as protection of the drug, enhanced …

Inorganic nanoparticles for cancer therapy: a transition from lab to clinic

S Bayda, M Hadla, S Palazzolo, P Riello… - Current medicinal …, 2018 - ingentaconnect.com
Background: Inorganic nanoparticles (NPs) including those derived from metals (eg, gold,
silver), semiconductors (eg, quantum dots), carbon dots, carbon nanotubes, or oxides (eg …

The blood–spinal cord barrier: morphology and clinical implications

V Bartanusz, D Jezova, B Alajajian… - Annals of …, 2011 - Wiley Online Library
The blood–spinal cord barrier (BSCB) is the functional equivalent of the blood–brain barrier
(BBB) in the sense of providing a specialized microenvironment for the cellular constituents …

Nanocarriers for the treatment of glioblastoma multiforme: current state-of-the-art

R Karim, C Palazzo, B Evrard, G Piel - Journal of controlled release, 2016 - Elsevier
Glioblastoma multiforme, a grade IV glioma, is the most frequently occurring and invasive
primary tumor of the central nervous system, which causes about 4% of cancer-associated …

From adsorption to covalent bonding: Apolipoprotein E functionalization of polymeric nanoparticles for drug delivery across the blood–brain barrier

N Hartl, F Adams, OM Merkel - Advanced therapeutics, 2021 - Wiley Online Library
The blood–brain barrier (BBB) is composed of brain endothelial cells, pericytes, and
astrocytes, which build a tight cellular barrier. Therapeutic (macro) molecules are not able to …

Designing the nanoparticle–biomolecule interface for “targeting and therapeutic delivery”

E Mahon, A Salvati, FB Bombelli, I Lynch… - Journal of Controlled …, 2012 - Elsevier
The endogenous transport mechanisms which occur in living organisms have evolved to
allow selective transport and processing operate on a scale of tens of nanometers. This …

[HTML][HTML] Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances

X Niu, J Chen, J Gao - Asian journal of pharmaceutical sciences, 2019 - Elsevier
Neurodegenerative diseases including Alzheimer's disease, Parkinson's disease,
Huntington disease and amyotrophic lateral sclerosis throw a heavy burden on families and …

[HTML][HTML] The nanomedicine revolution: part 1: emerging concepts

CL Ventola - Pharmacy and Therapeutics, 2012 - ncbi.nlm.nih.gov
The Nanomedicine Revolution - PMC Back to Top Skip to main content NIH NLM Logo Access
keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search PMC …

Exploiting intrinsic nanoparticle toxicity: the pros and cons of nanoparticle-induced autophagy in biomedical research

K Peynshaert, BB Manshian, F Joris… - Chemical …, 2014 - ACS Publications
1. INTRODUCTION In his 1959 keynote lecture “There is plenty of room at the bottom”,
Richard Feynman introduced the concepts that would later form the basis of a new era of …

Molecular communication and nanonetwork for targeted drug delivery: A survey

UAK Chude-Okonkwo, R Malekian… - … Surveys & Tutorials, 2017 - ieeexplore.ieee.org
Molecular communication (MC) and molecular network (MN) are communication paradigms
that use biochemical signaling to achieve information exchange among naturally and …