Nano-bio interactions: the implication of size-dependent biological effects of nanomaterials
Due to their many advantageous properties, nanomaterials (NMs) have been utilized in
diverse consumer goods, industrial products, and for therapeutic purposes. This situation …
diverse consumer goods, industrial products, and for therapeutic purposes. This situation …
[HTML][HTML] Recent advances in the development of nanomedicines for the treatment of ischemic stroke
Ischemic stroke is still a serious threat to human life and health, but there are few therapeutic
options available to treat stroke because of limited blood-brain penetration. The …
options available to treat stroke because of limited blood-brain penetration. The …
Noninvasive and targeted delivery of therapeutics to the brain using focused ultrasound
The range of therapeutic treatment options for central nervous system (CNS) diseases is
greatly limited by the blood-brain barrier (BBB). While a variety of strategies to circumvent …
greatly limited by the blood-brain barrier (BBB). While a variety of strategies to circumvent …
Biotransformation modulates the penetration of metallic nanomaterials across an artificial blood–brain barrier model
Understanding the potential of nanomaterials (NMs) to cross the blood–brain barrier (BBB),
as a function of their physicochemical properties and subsequent behavior, fate, and …
as a function of their physicochemical properties and subsequent behavior, fate, and …
Cancer stem cells in solid tumors
PC Hermann, S Bhaskar, M Cioffi… - Seminars in cancer biology, 2010 - Elsevier
According to the cancer progression model, several events are required for the progression
from normal epithelium to carcinoma. Due to their extended life span, stem cells would …
from normal epithelium to carcinoma. Due to their extended life span, stem cells would …
Perturbation of physiological systems by nanoparticles
Nanotechnology is having a tremendous impact on our society. However, societal concerns
about human safety under nanoparticle exposure may derail the broad application of this …
about human safety under nanoparticle exposure may derail the broad application of this …
Protein fibrillation and nanoparticle interactions: opportunities and challenges
Due to their ultra-small size, nanoparticles (NPs) have distinct properties compared with the
bulk form of the same materials. These properties are rapidly revolutionizing many areas of …
bulk form of the same materials. These properties are rapidly revolutionizing many areas of …
Biopolymer nanoparticles for nose-to-brain drug delivery: A new promising approach for the treatment of neurological diseases
Diseases affecting the central nervous system (CNS) are among the most disabling and the
most difficult to cure due to the presence of the blood–brain barrier (BBB) which represents …
most difficult to cure due to the presence of the blood–brain barrier (BBB) which represents …
Suitability of 3D human brain spheroid models to distinguish toxic effects of gold and poly-lactic acid nanoparticles to assess biocompatibility for brain drug delivery
Background The blood brain barrier (BBB) is the bottleneck of brain-targeted drug
development. Due to their physico-chemical properties, nanoparticles (NP) can cross the …
development. Due to their physico-chemical properties, nanoparticles (NP) can cross the …
[HTML][HTML] The nanomedicine revolution: part 2: current and future clinical applications
CL Ventola - Pharmacy and Therapeutics, 2012 - ncbi.nlm.nih.gov
Although many nanotherapeutic and nanodiagnostic agents are in use and have the
potential to improve health care, many barriers have impeded the development and …
potential to improve health care, many barriers have impeded the development and …