SPION-enhanced magnetic resonance imaging of Alzheimer's disease plaques in AβPP/PS-1 transgenic mouse brain

LO Sillerud, NO Solberg… - Journal of …, 2013 - content.iospress.com
In our program to develop non-invasive magnetic resonance imaging (MRI) methods for the
diagnosis of Alzheimer's disease (AD), we have synthesized antibody-conjugated …

Exosome mediated delivery of functional nucleic acid nanoparticles (NANPs)

S Nordmeier, W Ke, KA Afonin… - Therapeutic RNA …, 2021 - taylorfrancis.com
RNAi-based technologies have shown biomedical potential; however, safe and efficient
delivery of RNA remains a barrier for their broader clinical applications. Nucleic acid …

BBB-targeting, protein-based nanomedicines for drug and nucleic acid delivery to the CNS

H Peluffo, U Unzueta, ML Negro-Demontel, Z Xu… - Biotechnology …, 2015 - Elsevier
The increasing incidence of diseases affecting the central nervous system (CNS) demands
the urgent development of efficient drugs. While many of these medicines are already …

Multifunctional nanoparticles for dual imaging

Z Ali, AZ Abbasi, F Zhang, P Arosio… - Analytical …, 2011 - ACS Publications
For imaging with different modalities, labels, which provide contrast for all modalities, are
required. Colloidal nanoparticles composed out of an inorganic core and a polymer shell …

Targeting human brain cancer stem cells by curcumin-loaded nanoparticles grafted with anti-aldehyde dehydrogenase and sialic acid: Colocalization of ALDH and …

YC Kuo, LJ Wang, R Rajesh - Materials Science and Engineering: C, 2019 - Elsevier
The use of chemotherapy against brain tumors faces various limitations to achieving its
therapeutic effect, due to both the inability of anticancer agents to cross the blood–brain …

[PDF][PDF] A Review of Diagnostic Nano Stents: Part (I)

ARM Sikkander, H Yadav, M Meena, N Wahi… - J. Chem …, 2024 - researchgate.net
A Review of Diagnostic Nano Stents: Part (I) Page 1 2024, Volume 6, Issue 2 138 Journal of
Chemical Reviews *Corresponding Author: Abdul Razak Mohamed Sikkander (ams240868@gmail.com …

Nanoparticles approaches in neurodegenerative diseases diagnosis and treatment

Z Asefy, S Hoseinnejhad, Z Ceferov - Neurological Sciences, 2021 - Springer
Abstract The World Health Organization (WHO) has declared that neurodegenerative
diseases will be the biggest health issues of the twenty-first century. Among these …

Advances in targeted drug delivery approaches for the central nervous system tumors: the inspiration of nanobiotechnology

J Meng, V Agrahari, I Youm - Journal of Neuroimmune Pharmacology, 2017 - Springer
At present, brain tumor is among the most challenging diseases to treat and the therapy is
limited by the lack of effective methods to deliver anticancer agents across the blood-brain …

Simulation of adsorption and release of doxepin onto ZIF-8 including in vitro cellular toxicity and viability

X Dou, M Keywanlu, R Tayebee, B Mahdavi - Journal of Molecular Liquids, 2021 - Elsevier
Doxepin hydrochloride is an antidepressant drug commonly used to treat mild to moderate
depression. However, this drug has poor oral bioavailability, with the percentage of drug that …

Enhanced permeability of blood–brain barrier and targeting function of brain via borneol-modified chemically solid lipid nanoparticle

H Song, M Wei, N Zhang, H Li, X Tan… - International journal …, 2018 - Taylor & Francis
Introduction The incidence of central nervous system disease has increased in recent years.
However, the transportation of drug is restricted by the blood–brain barrier, contributing to …