Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines

A Sette, S Crotty - Immunological reviews, 2022 - Wiley Online Library
Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

Correlates of protection against SARS‐CoV‐2 infection and COVID‐19 disease

D Goldblatt, G Alter, S Crotty… - Immunological reviews, 2022 - Wiley Online Library
Antibodies against epitopes in S1 give the most accurate CoP against infection by the SARS‐
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …

T cells in health and disease

L Sun, Y Su, A Jiao, X Wang, B Zhang - Signal transduction and …, 2023 - nature.com
T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity

O Cabral-Marques, G Halpert, LF Schimke… - Nature …, 2022 - nature.com
COVID-19 shares the feature of autoantibody production with systemic autoimmune
diseases. In order to understand the role of these immune globulins in the pathogenesis of …

SARS-CoV-2-specific T cells associate with inflammation and reduced lung function in pulmonary post-acute sequalae of SARS-CoV-2

KM Littlefield, RO Watson, JM Schneider… - PLoS …, 2022 - journals.plos.org
As of January 2022, at least 60 million individuals are estimated to develop post-acute
sequelae of SARS-CoV-2 (PASC) after infection with severe acute respiratory syndrome …

Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity

C Riou, R Keeton, T Moyo-Gwete… - Science translational …, 2021 - science.org
SARS-CoV-2 variants that escape neutralization and potentially affect vaccine efficacy have
emerged. T cell responses play a role in protection from reinfection and severe disease, but …

COVID‐19 immunopathology: from acute diseases to chronic sequelae

M Arish, W Qian, H Narasimhan… - Journal of medical …, 2023 - Wiley Online Library
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …

[HTML][HTML] Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly

IATM Ferreira, CYC Lee, WS Foster, A Abdullahi… - Cell Reports, 2023 - cell.com
Suboptimal responses to a primary vaccination course have been reported in the elderly, but
there is little information regarding the impact of age on responses to booster third doses …

Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

Spotlight on therapeutic efficiency of mesenchymal stem cells in viral infections with a focus on COVID-19

S Yasamineh, HG Kalajahi, P Yasamineh… - Stem Cell Research & …, 2022 - Springer
The SARS-COV-2 virus has infected the world at a very high rate by causing COVID-19
disease. Nearly 507 million individuals have been infected with this virus, with …