NAD+ metabolism, stemness, the immune response, and cancer
LE Navas, A Carnero - Signal transduction and targeted therapy, 2021 - nature.com
NAD+ was discovered during yeast fermentation, and since its discovery, its important roles
in redox metabolism, aging, and longevity, the immune system and DNA repair have been …
in redox metabolism, aging, and longevity, the immune system and DNA repair have been …
Emerging roles of SIRT6 in human diseases and its modulators
The biological functions of sirtuin 6 (SIRT6; eg, deacetylation, defatty‐acylation, and mono‐
ADP‐ribosylation) play a pivotal role in regulating lifespan and several fundamental …
ADP‐ribosylation) play a pivotal role in regulating lifespan and several fundamental …
Dual tumor suppressor and tumor promoter action of sirtuins in determining malignant phenotype
V Carafa, L Altucci, A Nebbioso - Frontiers in pharmacology, 2019 - frontiersin.org
Sirtuins (SIRTs), class III histone deacetylases, are differentially expressed in several human
cancers, where they display both oncogenic and tumor-suppressive properties depending …
cancers, where they display both oncogenic and tumor-suppressive properties depending …
A comprehensive analysis into the therapeutic application of natural products as SIRT6 modulators in Alzheimer's disease, aging, cancer, inflammation, and diabetes
Natural products have long been used as drugs to treat a wide array of human diseases.
The lead compounds discovered from natural sources are used as novel templates for …
The lead compounds discovered from natural sources are used as novel templates for …
Cryo-EM structure of the human Sirtuin 6–nucleosome complex
Sirtuin 6 (SIRT6) is a multifaceted protein deacetylase/deacylase and a major target for
small-molecule modulators of longevity and cancer. In the context of chromatin, SIRT6 …
small-molecule modulators of longevity and cancer. In the context of chromatin, SIRT6 …
Review of palm vein recognition
As a new research focus in biometrics, palm vein recognition has attracted people's attention
because of high security, liveness‐detection, user acceptability and convenience. Palm vein …
because of high security, liveness‐detection, user acceptability and convenience. Palm vein …
A systematic review on physiological-based biometric recognition systems: current and future trends
Biometric deals with the verification and identification of a person based on behavioural and
physiological traits. This article presents recent advances in physiological-based biometric …
physiological traits. This article presents recent advances in physiological-based biometric …
SIRT6 in senescence and aging-related cardiovascular diseases
X Li, L Liu, T Li, M Liu, Y Wang, H Ma, N Mu… - Frontiers in cell and …, 2021 - frontiersin.org
SIRT6 belongs to the nicotinamide adenine dinucleotide (NAD+)-dependent deacetylases
and has established diverse roles in aging, metabolism and disease. Its function is similar to …
and has established diverse roles in aging, metabolism and disease. Its function is similar to …
[HTML][HTML] The “ART” of epigenetics in melanoma: from histone “alterations, to resistance and therapies”
Malignant melanoma is the most deadly form of skin cancer. It originates from melanocytic
cells and can also arise at other body sites. Early diagnosis and appropriate medical care …
cells and can also arise at other body sites. Early diagnosis and appropriate medical care …
Subcellular compartmentalization of NAD+ and its role in cancer: A sereNADe of metabolic melodies
Y Zhu, J Liu, J Park, P Rai, RG Zhai - Pharmacology & therapeutics, 2019 - Elsevier
Nicotinamide adenine dinucleotide (NAD+) is an essential biomolecule involved in many
critical processes. Its role as both a driver of energy production and a signaling molecule …
critical processes. Its role as both a driver of energy production and a signaling molecule …