Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Water transport between CNS compartments: functional and molecular interactions between aquaporins and ion channels

V Benfenati, S Ferroni - Neuroscience, 2010 - Elsevier
The physiological ability of the mammalian CNS to integrate peripheral stimuli and to convey
information to the body is tightly regulated by its capacity to preserve the ion composition …

Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouse

SC Azad, M Eder, G Marsicano, B Lutz… - Learning & …, 2003 - learnmem.cshlp.org
The endogenous cannabinoid system has been shown recently to play a crucial role in the
extinction of aversive memories. As the amygdala is presumably involved in this process, we …

Radial stem astrocytes (aka neural stem cells): identity, development, physio‐pathology, and therapeutic potential

CY Yeh, KY Wu, GJ Huang, A Verkhratsky - Acta Physiologica, 2023 - Wiley Online Library
Adult neurogenesis is a striking example of neuroplasticity, which enables adaptive network
remodelling in response to all forms of environmental stimulation in physiological and …

Potassium dynamics and seizures: Why is potassium ictogenic?

M de Curtis, L Uva, V Gnatkovsky, L Librizzi - Epilepsy research, 2018 - Elsevier
Potassium channels dysfunction and altered genes encoding for molecules involved in
potassium homeostasis have been associated with human epilepsy. These observations are …

A silk platform that enables electrophysiology and targeted drug delivery in brain astroglial cells

V Benfenati, S Toffanin, R Capelli, LMA Camassa… - Biomaterials, 2010 - Elsevier
Astroglial cell survival and ion channel activity are relevant molecular targets for the
mechanistic study of neural cell interactions with biomaterials and/or electronic interfaces …

Freshly Isolated Astrocytes From Rat Hippocampus Show Two Distinct Current Patterns and Different [K+]oUptake Capabilities

M Zhou, HK Kimelberg - Journal of neurophysiology, 2000 - journals.physiology.org
Whether astrocytes predominantly express ohmic K+ channels in vivo, and how expression
of different K+ channels affects [K+] ohomeostasis in the CNS have been long-standing …

The expression and activity of KV3. 4 channel subunits are precociously upregulated in astrocytes exposed to Aβ oligomers and in astrocytes of Alzheimer's disease …

F Boscia, A Pannaccione, R Ciccone, A Casamassa… - Neurobiology of …, 2017 - Elsevier
Astrocyte dysfunction emerges early in Alzheimer's disease (AD) and may contribute to its
pathology and progression. Recently, the voltage gated potassium channel KV 3.4 subunit …

Kir and Kv channels regulate electrical properties and proliferation of adult neural precursor cells

T Yasuda, PF Bartlett, DJ Adams - Molecular and Cellular Neuroscience, 2008 - Elsevier
The functional significance of the electrophysiological properties of neural precursor cells
(NPCs) was investigated using dissociated neurosphere-derived NPCs from the forebrain …

Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdala

SC Azad, J Kurz, G Marsicano, B Lutz… - Learning & …, 2008 - learnmem.cshlp.org
Previously, we found that in the lateral amygdala (LA) of the mouse, WIN55, 212-2
decreases both glutamatergic and GABAergic synaptic transmission via activation of the …