Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics

E Wyler, JM Adler, K Eschke, GT Alves, S Peidli, F Pott… - Molecular Therapy, 2022 - cell.com
For coronavirus disease 2019 (COVID-19), effective and well-understood treatment options
are still scarce. Since vaccine efficacy is challenged by novel variants, short-lasting …

[HTML][HTML] Natural tannins as anti-SARS-CoV-2 compounds

SC Wang, IW Chou, MC Hung - International Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Tannins are polyphenols enriched in wood, bark, roots, leaves, seeds and fruits of a variety
of plants. Over the last two decades, there has been an increasing interest in understanding …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

Antiviral phytocompounds “ellagic acid” and “(+)-sesamin” of Bridelia retusa identified as potential inhibitors of SARS-CoV-2 3CL pro using extensive molecular …

AK Umar, JH Zothantluanga, K Aswin, S Maulana… - Structural …, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected billions and
has killed millions to date. Studies are being carried out to find therapeutic molecules that …

Mitigation of influenza-mediated inflammation by immunomodulatory matrix-bound nanovesicles

RJ Crum, BR Huckestien, G Dwyer, L Mathews… - Science …, 2023 - science.org
Cytokine storm describes a life-threatening, systemic inflammatory syndrome characterized
by elevated levels of proinflammatory cytokines and immune cell hyperactivation associated …

Interleukin-18 is a potential biomarker to discriminate active adult-onset still's disease from COVID-19

PK Chen, JL Lan, PH Huang, JL Hsu… - Frontiers in …, 2021 - frontiersin.org
Background Hyperinflammation with dysregulated production of galectins and cytokines
may develop in COVID-19 or adult-onset Still's disease (AOSD). Given the similar clinical …

RETRACTED: Artemisia Extracts and Artemisinin-Based Antimalarials for COVID-19 Management: Could These Be Effective Antivirals for COVID-19 Treatment?

PK Agrawal, C Agrawal, G Blunden - Molecules, 2022 - mdpi.com
As the world desperately searches for ways to treat the coronavirus disease 2019 (COVID-
19) pandemic, a growing number of people are turning to herbal remedies. The Artemisia …

[PDF][PDF] Be aware of SARS-CoV-2 spike protein: There is more than meets the eye

TC Theoharides, P Conti - J Biol Regul Homeost Agents, 2021 - mastcellmaster.com
The COVID-19 pandemic necessitated the rapid production of vaccines aimed at the
production of neutralizing antibodies against the COVID-19 spike protein required for the …

Discovery and repurposing of artemisinin

Q Shi, F Xia, Q Wang, F Liao, Q Guo, C Xu, J Wang - Frontiers of medicine, 2022 - Springer
Malaria is an ancient infectious disease that threatens millions of lives globally even today.
The discovery of artemisinin, inspired by traditional Chinese medicine (TCM), has brought in …

[HTML][HTML] The effectiveness of high-dose intravenous vitamin C for patients with coronavirus disease 2019: a systematic review and meta-analysis

SG Kwak, YJ Choo, MC Chang - Complementary therapies in medicine, 2022 - Elsevier
Objectives Vitamin C has anti-inflammatory effects. This review aimed to investigate the
therapeutic effect of high-dose intravenous vitamin C (HDIVC) in patients with coronavirus …