Background Low aerobic capacity is associated with an increased mortality risk in allogenic
stem-cell transplantation (alloSCT) patients, but currently used risk scores in the pre …

Описана клиническая картина “цитокинового шторма” на примере последствий
введения экспериментального препарата TGN1412 здоровым волонтерам в марте …

Allogeneic hematopoietic cell transplantation has developed into a most successful form of
immunotherapy for hematologic malignancies in the past 50 years. However, its …

Summary Proteinase inhibitor 9 (PI-9) is an intracellular serpin expressed in lymphocytes
and monocyte-derived cells. It is the only known endogenous natural antagonist of …

Abstract Background Veno-occlusive disease, Graft-versus-Host disease, invasive or
localized bacterial, viral and fungal infections are known as adverse events after …

Diagnosis of adverse events following hematopoietic stem cell transplantation (HSCT) is
mainly assigned to clinical symptoms or biopsies and thus rather unspecific and/or invasive …

Background: Graft versus host disease (GVHD) is a significant complication following
hematopoietic stem cell transplantation in the pediatric population. The most common …

Background. Based on experimental models, chronic graft-versus-host disease (cGVHD)
may depend on activated donor antigen-presenting cells presenting host antigens to donor …

In the past decade the field of hematopoietic stem cell transplantation has entered a new era
with the introduction of reduced intensity conditioning (RIC) regimens. The impact of RIC on …

The human leukocyte antigen DR surface expression on CD14+ monocytes reflects the
degree to which these cells have been activated. Given the central role monocytes and …