Clinical utility of mesenchymal stem/stromal cells in regenerative medicine and cellular therapy

VV Maldonado, NH Patel, EE Smith, CL Barnes… - Journal of biological …, 2023 - Springer
Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous
potential in regenerative medicine. With their immunomodulatory and regenerative …

The potential use of mesenchymal stem cells and their exosomes in Parkinson's disease treatment

RM Heris, M Shirvaliloo, S Abbaspour-Aghdam… - Stem Cell Research & …, 2022 - Springer
Parkinson's disease (PD) is the second most predominant neurodegenerative disease
worldwide. It is recognized clinically by severe complications in motor function caused by …

Role of exosomes in the pathogenesis of inflammation in Parkinson's disease

KL Li, HY Huang, H Ren, XL Yang - Neural regeneration research, 2022 - journals.lww.com
Inflammatory responses, including glial cell activation and peripheral immune cell infiltration,
are involved in the pathogenesis of Parkinson's disease (PD). These inflammatory …

[HTML][HTML] Mesenchymal stem cells-derived extracellular vesicles ameliorate Alzheimer's disease in rat models via the microRNA-29c-3p/BACE1 axis and the Wnt/β …

S Sha, X Shen, Y Cao, L Qu - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Currently, Alzheimer's disease (AD) cannot be treated effectively. Mesenchymal stem cells
(MSCs)-derived extracellular vesicles (EVs)(MSC-EVs) exhibit therapeutic effects on many …

[HTML][HTML] Translational insights into stem cell preconditioning: from molecular mechanisms to preclinical applications

K Moeinabadi-Bidgoli, A Babajani… - Biomedicine & …, 2021 - Elsevier
Cell-based therapy (CBT) is a revolutionary approach for curing a variety of degenerative
diseases. Stem cell-based regenerative medicine is a novel strategy for treating tissue …

Stem cell-based therapies for Parkinson disease

Z Liu, HH Cheung - International journal of molecular sciences, 2020 - mdpi.com
Parkinson disease (PD) is a neurological movement disorder resulting primarily from
damage to and degeneration of the nigrostriatal dopaminergic pathway. The pathway …

Mindfulness and other simple neuroscience-based proposals to promote the learning performance and mental health of students during the COVID-19 pandemic

GR Tortella, AB Seabra, J Padrao, R Diaz-San Juan - Brain sciences, 2021 - mdpi.com
The COVID-19 pandemic has had a negative impact on education. The restrictions imposed
have undoubtedly led to impairment of the psychological well-being of both teachers and …

Mesenchymal stem cell-derived exosomes as new remedy for the treatment of neurocognitive disorders

CR Harrell, A Volarevic, V Djonov… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cell (MSC)-derived exosomes (MSC-Exo) are nano-sized extracellular
vesicles enriched with MSC-sourced neuroprotective and immunomodulatory microRNAs …

Extracellular vesicles of mesenchymal stem cells: therapeutic properties discovered with extraordinary success

G Racchetti, J Meldolesi - Biomedicines, 2021 - mdpi.com
Mesenchymal stem cells (MSCs), the cells distributed in the stromas of the body, are known
for various properties including replication, the potential of various differentiations, the …

[HTML][HTML] MSC-derived exosomes can enhance the angiogenesis of human brain MECs and show therapeutic potential in a mouse model of Parkinson's disease

C Xue, X Li, L Ba, M Zhang, Y Yang, Y Gao… - Aging and …, 2021 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is the second most widespread neurodegenerative disorder in the
world. It has been reported that exosomes derived from mesenchymal stem cells (MSCs) …