Crosstalk among circRNA/lncRNA, miRNA, and mRNA in osteoarthritis

H Kong, ML Sun, XA Zhang, XQ Wang - Frontiers in Cell and …, 2021 - frontiersin.org
Osteoarthritis (OA) is a joint disease that is pervasive in life, and the incidence and mortality
of OA are increasing, causing many adverse effects on people's life. Therefore, it is very vital …

The emerging role of lncRNAs in osteoarthritis development and potential therapy

X Zhang, Q Liu, J Zhang, C Song, Z Han, J Wang… - Frontiers in …, 2023 - frontiersin.org
Osteoarthritis impairs the functions of various joints, such as knees, hips, hands and spine,
which causes pain, swelling, stiffness and reduced mobility in joints. Multiple factors …

LncRNA CASC19 enhances the radioresistance of nasopharyngeal carcinoma by regulating the miR-340-3p/FKBP5 axis

H Liu, Q Chen, W Zheng, Y Zhou, Y Bai, Y Pan… - International journal of …, 2023 - mdpi.com
Radioresistance remains a serious obstacle encountered in the radiotherapy of
nasopharyngeal carcinoma (NPC). Both mRNAs and non-coding RNAs (ncRNAs), including …

Emerging role of lncRNAs in osteoarthritis: An updated review

R Wang, HT Shiu, WYW Lee - Frontiers in immunology, 2022 - frontiersin.org
Osteoarthritis (OA) is a prevalent joint disease, which is associated with progressive articular
cartilage loss, synovial inflammation, subchondral sclerosis and meniscus injury. The …

Circulating exosomal circRNA_0063476 impairs expression of markers of bone growth via the miR-518c-3p/DDX6 Axis in ISS

Z Du, J Yuan, Z Wu, Q Chen, X Liu, J Jia - Endocrinology, 2022 - academic.oup.com
Objectives Idiopathic short stature (ISS), a disorder of unknown cause, accounts for
approximately 80% of the clinical diagnoses of children with short stature. Exosomal circular …

Non‐coding RNAs in diseases with a focus on osteoarthritis

A Pekáčová, J Baloun, X Švec… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Osteoarthritis (OA) is a frequent musculoskeletal disorder affecting millions of people
worldwide. Despite advances in understanding the pathogenesis of OA, prognostic …

MicroRNA152-3p Protects Against Ischemia/Reperfusion-Induced Bbb Destruction Possibly Targeting the MAP3K2/JNK/c-Jun Pathway

F Li, F Zhou, B Yang - Neurochemical Research, 2023 - Springer
In the current study, we reported that overexpression of miR-152-3p effectively ameliorated
neurological deficits and protected blood-brain barrier (BBB) integrity in middle cerebral …

Unraveling the Molecular Landscape of Osteoarthritis: A Comprehensive Review Focused on the Role of Non-Coding RNAs

M Shakeri, A Aminian, K Mokhtari, M Bahaeddini… - … -Research and Practice, 2024 - Elsevier
Osteoarthritis (OA) poses a significant global health challenge, with its prevalence
anticipated to increase in the coming years. This review delves into the emerging molecular …

DDX6 通过调控CKMT1A mRNA 稳定性促进鼻咽癌细胞增殖和迁移的机制研究

熊茄妍, 雷伟, 游波, 张振新, 谢海静, 单颖… - 中国癌症 …, 2024 - china-oncology.com
背景与目的: DDX 是一类腺苷三磷酸(adenosine triphosphate, ATP) 依赖的RNA 解旋酶,
与mRNA 调控, 肿瘤增殖及侵袭等密切相关. 本研究旨在探讨DDX 家族成员DDX6 对CKMT1A …

Advances in Research on the Regulatory Roles of lncRNAs in Osteoarthritic Cartilage

J Wu, Z Zhang, X Ma, X Liu - Biomolecules, 2023 - mdpi.com
Osteoarthritis (OA) is the most common degenerative bone and joint disease that can lead to
disability and severely affect the quality of life of patients. However, its etiology and …