[HTML][HTML] The development of New Delhi metallo-β-lactamase-1 inhibitors since 2018

X Gu, M Zheng, L Chen, H Li - Microbiological Research, 2022 - Elsevier
New Delhi metallo-β-lactamase-1 (NDM-1) can hydrolyze almost all antibiotics of the β-
lactam group, resulting in the generation of multidrug resistant bacteria. Besides its broad …

New silver (I) complex as antibiotic candidate: synthesis, spectral characterization, DFT, QTAIM and antibacterial investigations and docking properties

S Celik, S Yurdakul, B Erdem - Journal of Molecular Structure, 2022 - Elsevier
In the present work, a newly synthesized silver (I) complex was characterized using
elemental analysis, UV–Vis spectroscopy, and infrared spectroscopy. DFT calculations at …

[HTML][HTML] Cadmium stress efficiently enhanced meropenem degradation by the meropenem-and cadmium-resistant strain Pseudomonas putida R51

C Zhong, Y Zhou, J Fu, X Qi, Z Wang, J Li… - Journal of Hazardous …, 2022 - Elsevier
The β-lactam antibiotic meropenem (MEM) is widely used in infectious disease treatment
and consequently can be released into the environment, causing environmental pollution. In …

Synthesis and in silico evaluation of novel uridyl sulfamoylbenzoate derivatives as potential anticancer agents targeting M1 subunit of human ribonucleotide reductase …

PJ Salvador, HB Jacobs, L Alnouri, A Fee… - Medicinal Chemistry …, 2022 - Springer
Ribonucleotide reductase (RNR) is a key target in cancer chemotherapy. The enzyme
catalyzes reduction of ribonucleotides to 2′-deoxyribonucleotides and its activity is rate …