Efficient proteostasis is crucial for somatic maintenance, and its decline during aging leads
to cellular dysfunction and disease. Selective autophagy is a form of autophagy mediated by …

Inflammation, when properly mounted and precisely calibrated, is a beneficial process that
enables the rapid removal of invading pathogens and/or cellular corpses and promotes …

Our understanding of stress granule (SG) biology has deepened considerably in recent
years, and with this, increased understanding of links has been made between SGs and …

Non-alcoholic fatty liver disease (NAFLD) describes a steatotic (or fatty) liver occurring as a
consequence of a combination of metabolic, environmental, and genetic factors, in the …

Doxorubicin (DOX) is a potent chemotherapeutic agent used against several cancer types.
However, due to its cardiotoxic adverse effects, the use of this drug may be also life …

Ethnopharmacological relevance Panax japonicus (T. Nees) CA Mey.(PJ) has been used as
a tonic traditional Chinese medicine (TCM) for years. Based on its meridian tropism in liver …

The development and progression of cancer are associated with the dysregulation of
multiple pathways involved in cell proliferation and survival, as well as dysfunction in redox …

NLRP1 is the primary inflammasome sensor in human keratinocytes. Sensing of UVB
radiation by NLRP1 is believed to underlie the induction of sunburn. Although constitutive …

Breast cancer has become the most prevalent cancer, globally. Adriamycin is a first-line
chemotherapeutic agent, however, cancer cells acquire resistance to it, which is one of the …

Simple Summary Hepatocellular carcinoma (HCC) is a major health problem with the
second highest mortality among all cancers and a continuous increase worldwide. HCC is …